Hu Yunfei, Byrne Mikel, Archibald-Heeren Ben, Squires Matthew, Teh Amy, Seiffert Kylie, Cheers Sonja, Wang Yang
Radiation Oncology Centres, Gosford, NSW, Australia.
Radiation Oncology Centres, Wahroonga, NSW, Australia.
J Med Phys. 2017 Jul-Sep;42(3):163-170. doi: 10.4103/jmp.JMP_32_17.
Dedicated rapid access palliative radiation therapy improves patients' access to care, allowing more timely treatment which would positively impact on quality of life. The TomoTherapy (Accuray, Sunnyvale, CA) system provides megavoltage (MV) fan-beam computed tomography (FBCT) as the image guidance technique, and a module called "statRT" that allows the use of these MV FBCT images for direct planning. The possibility of using this imaging modality for palliative radiotherapy treatment planning is assessed against accepted planning CT standards by performing tests following AAPM TG 66 and an end-to-end measurement. Results have shown that MV FBCT images acquired by TomoTherapy are of sufficient quality for the purpose of target delineation and dose calculation for palliative treatments. Large image noise and extended scan acquisition time are the two main drawbacks, so this imaging modality should only be used for palliative treatments at areas with well-known, easily distinguishable, and relatively immobile targets such as spine and whole brain.
专用快速姑息性放射治疗改善了患者获得治疗的机会，使治疗更加及时，这将对生活质量产生积极影响。螺旋断层放疗系统（TomoTherapy，Accuray公司，加利福尼亚州桑尼维尔市）提供兆伏级（MV）扇形束计算机断层扫描（FBCT）作为图像引导技术，以及一个名为“statRT”的模块，该模块允许使用这些MV FBCT图像进行直接计划。通过按照美国医学物理师协会（AAPM）TG 66进行测试和进行端到端测量，对照公认的计划CT标准评估了将这种成像方式用于姑息性放射治疗计划的可能性。结果表明，螺旋断层放疗系统获取的MV FBCT图像对于姑息治疗的靶区勾画和剂量计算而言质量足够。较大的图像噪声和较长的扫描采集时间是两个主要缺点，因此这种成像方式仅应用于靶区已知、易于区分且相对固定的部位，如脊柱和全脑的姑息治疗。
