Department of Gastrointestinal and Anal Surgery, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Division of Clinical Research, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
World J Gastroenterol. 2017 Sep 14;23(34):6350-6356. doi: 10.3748/wjg.v23.i34.6350.
To identify which technique is better for avoiding biliary reflux and gastritis between uncut Roux-en-Y and Billroth II reconstruction.
A total of 158 patients who underwent laparoscopy-assisted distal gastrectomy for gastric cancer at the First Hospital of Jilin University (Changchun, China) between February 2015 and February 2016 were randomized into two groups: uncut Roux-en-Y (group U) and Billroth II group (group B). Postoperative complications and relevant clinical data were compared between the two groups.
According to the randomization table, each group included 79 patients. There was no significant difference in postoperative complications between groups U and B (7.6% 10.1%, = 0.576). During the postoperative period, group U stomach pH values were lower than 7 and group B pH values were higher than 7. After 1 year of follow-up, group B presented a higher incidence of biliary reflux and alkaline gastritis. However, histopathology did not show a significant difference in gastritis diagnosis ( = 0.278), and the amount of residual food and gain of weight between the groups were also not significantly different. At 3 mo there was no evidence of partial recanalization of uncut staple line, but at 1 year the incidence was 13%.
Compared with Billroth II reconstruction, uncut Roux-en-Y reconstruction is secure and feasible, and can effectively reduce the incidence of alkaline reflux, residual gastritis, and heartburn. Despite the incidence of recanalization, uncut Roux-en-Y should be widely applied.
明确在非离断 Roux-en-Y 与 Billroth II 重建中,哪种技术更能避免胆汁反流和胃炎。
选择 2015 年 2 月至 2016 年 2 月在吉林大学第一医院接受腹腔镜辅助远端胃癌根治术的 158 例患者,随机分为两组:非离断 Roux-en-Y 组(U 组)和 Billroth II 组(B 组)。比较两组患者术后并发症及相关临床资料。
根据随机数字表,每组各 79 例。U 组和 B 组术后并发症发生率差异无统计学意义(7.6%比 10.1%, = 0.576)。术后 U 组胃 pH 值低于 7,B 组 pH 值高于 7。随访 1 年,B 组发生胆汁反流和碱性胃炎的比例较高。但组织病理学检查示胃炎诊断差异无统计学意义( = 0.278),两组间残胃量和体质量增加也无显著差异。术后 3 个月未见非离断吻合钉线结部分再通,但术后 1 年再通发生率为 13%。
与 Billroth II 重建相比,非离断 Roux-en-Y 重建安全可行,能有效降低碱性反流、残胃炎和烧心的发生率。尽管存在吻合钉线结再通,但非离断 Roux-en-Y 仍应广泛应用。