Suppr超能文献

远端胃癌根治术后 Roux-en-Y 非离断式 Billroth II 重建术与 Roux-en-Y 离断式 Billroth II 重建术随机对照研究:哪种技术更能避免胆汁反流性胃炎?

Randomized controlled trial of uncut Roux-en-Y Billroth II reconstruction after distal gastrectomy for gastric cancer: Which technique is better for avoiding biliary reflux and gastritis?

机构信息

Department of Gastrointestinal and Anal Surgery, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

Division of Clinical Research, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

出版信息

World J Gastroenterol. 2017 Sep 14;23(34):6350-6356. doi: 10.3748/wjg.v23.i34.6350.

Abstract

AIM

To identify which technique is better for avoiding biliary reflux and gastritis between uncut Roux-en-Y and Billroth II reconstruction.

METHODS

A total of 158 patients who underwent laparoscopy-assisted distal gastrectomy for gastric cancer at the First Hospital of Jilin University (Changchun, China) between February 2015 and February 2016 were randomized into two groups: uncut Roux-en-Y (group U) and Billroth II group (group B). Postoperative complications and relevant clinical data were compared between the two groups.

RESULTS

According to the randomization table, each group included 79 patients. There was no significant difference in postoperative complications between groups U and B (7.6% 10.1%, = 0.576). During the postoperative period, group U stomach pH values were lower than 7 and group B pH values were higher than 7. After 1 year of follow-up, group B presented a higher incidence of biliary reflux and alkaline gastritis. However, histopathology did not show a significant difference in gastritis diagnosis ( = 0.278), and the amount of residual food and gain of weight between the groups were also not significantly different. At 3 mo there was no evidence of partial recanalization of uncut staple line, but at 1 year the incidence was 13%.

CONCLUSION

Compared with Billroth II reconstruction, uncut Roux-en-Y reconstruction is secure and feasible, and can effectively reduce the incidence of alkaline reflux, residual gastritis, and heartburn. Despite the incidence of recanalization, uncut Roux-en-Y should be widely applied.

摘要

目的

明确在非离断 Roux-en-Y 与 Billroth II 重建中,哪种技术更能避免胆汁反流和胃炎。

方法

选择 2015 年 2 月至 2016 年 2 月在吉林大学第一医院接受腹腔镜辅助远端胃癌根治术的 158 例患者,随机分为两组:非离断 Roux-en-Y 组(U 组)和 Billroth II 组(B 组)。比较两组患者术后并发症及相关临床资料。

结果

根据随机数字表,每组各 79 例。U 组和 B 组术后并发症发生率差异无统计学意义(7.6%比 10.1%, = 0.576)。术后 U 组胃 pH 值低于 7,B 组 pH 值高于 7。随访 1 年,B 组发生胆汁反流和碱性胃炎的比例较高。但组织病理学检查示胃炎诊断差异无统计学意义( = 0.278),两组间残胃量和体质量增加也无显著差异。术后 3 个月未见非离断吻合钉线结部分再通,但术后 1 年再通发生率为 13%。

结论

与 Billroth II 重建相比,非离断 Roux-en-Y 重建安全可行,能有效降低碱性反流、残胃炎和烧心的发生率。尽管存在吻合钉线结再通,但非离断 Roux-en-Y 仍应广泛应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c2/5603502/c54e7cd76a42/WJG-23-6350-g001.jpg

相似文献

2
Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer.
Cochrane Database Syst Rev. 2024 Feb 29;2(2):CD015014. doi: 10.1002/14651858.CD015014.pub2.
7
A 3-year follow-up study of uncut Roux-en-Y reconstruction: clinical results and outcomes.
Surg Endosc. 2022 Oct;36(10):7588-7596. doi: 10.1007/s00464-022-09198-7. Epub 2022 Apr 5.
8
Optimal Reconstruction After Laparoscopic Distal Gastrectomy: A Single-Center Retrospective Study.
Cancer Control. 2022 Jan-Dec;29:10732748221087059. doi: 10.1177/10732748221087059.
9
Comparison Between Billroth-II with Braun and Roux-en-Y Reconstruction After Laparoscopic Distal Gastrectomy.
J Gastrointest Surg. 2016 Jun;20(6):1083-90. doi: 10.1007/s11605-016-3138-7. Epub 2016 Apr 11.

引用本文的文献

2
Gastroduodenal intussusception: two cases of gastroduodenal intussusception following gastric plication, each managed with a different approach: a case report.
Ann Med Surg (Lond). 2025 Feb 11;87(2):1057-1064. doi: 10.1097/MS9.0000000000002946. eCollection 2025 Feb.
3
Current clinical trials on gastric cancer surgery in China.
World J Gastrointest Oncol. 2024 Nov 15;16(11):4369-4382. doi: 10.4251/wjgo.v16.i11.4369.
5
How to identify early complications in patients undergoing distal gastrectomy?
World J Gastrointest Surg. 2024 Apr 27;16(4):974-981. doi: 10.4240/wjgs.v16.i4.974.
6
Comparison of uncut Roux-en-Y anastomosis and Billroth-II with Braun anastomosis after distal gastrectomy.
Front Surg. 2024 Mar 28;11:1390876. doi: 10.3389/fsurg.2024.1390876. eCollection 2024.
7
Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer.
Cochrane Database Syst Rev. 2024 Feb 29;2(2):CD015014. doi: 10.1002/14651858.CD015014.pub2.
9
Uncut Roux-en-Y gastrojejunostomy after totally laparoscopic distal gastrectomy: Learning curve and surgical outcomes.
Korean J Clin Oncol. 2020 Jun;16(1):46-51. doi: 10.14216/kjco.20008. Epub 2020 Jun 30.
10
Global scientific trends in laparoscopy and gastric cancer in the 21st century: A bibliometric and visual mapping analysis.
Front Oncol. 2023 Feb 23;13:1136834. doi: 10.3389/fonc.2023.1136834. eCollection 2023.

本文引用的文献

1
Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer.
Expert Rev Gastroenterol Hepatol. 2016 Dec;10(12):1341-1347. doi: 10.1080/17474124.2016.1248404. Epub 2016 Oct 27.
3
To Roux or not to Roux: a comparison between Roux-en-Y and Billroth II reconstruction following partial gastrectomy for gastric cancer.
Gastric Cancer. 2016 Jul;19(3):994-1001. doi: 10.1007/s10120-015-0547-3. Epub 2015 Sep 23.
7
What is the best reconstruction method after distal gastrectomy for gastric cancer?
Surg Endosc. 2012 Jun;26(6):1539-47. doi: 10.1007/s00464-011-2064-8. Epub 2011 Dec 17.
9
Myoelectric activity and motility of the Roux limb after cut or uncut Roux-en-Y gastrojejunostomy.
World J Gastroenterol. 2006 Dec 21;12(47):7699-704. doi: 10.3748/wjg.v12.i47.7699.
10
Laparoscopy-assisted uncut Roux-en-Y operation after distal gastrectomy for gastric cancer.
Gastric Cancer. 2005;8(4):253-7. doi: 10.1007/s10120-005-0344-5.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验