Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, 50603, Malaysia.
Department of Metallurgical Engineering, Faculty of Chemical and Process Engineering, NED University of Engineering and Technology, Karachi, 75270, Pakistan.
J Biomed Mater Res A. 2018 Feb;106(2):590-605. doi: 10.1002/jbm.a.36259. Epub 2017 Oct 30.
Plasma electrolytic oxidation (PEO) is an advance technique to develop porous oxidation layer on light metals, primarily to enhance corrosion and wear resistance. The oxidation layer can also offer a wide variety of mechanical, biomedical, tribological, and antibacterial properties through the incorporation of several ions and particles. Due to the increasing need of antimicrobial surfaces for biomedical implants, antibacterial PEO coatings have been developed through the incorporation of antibacterial agents. Metallic nanoparticles that have been employed most widely as antibacterial agents are reported to demonstrate serious health and environmental threats. To overcome the current limitations of these coatings, there is a significant need to develop antibacterial surfaces that are not harmful for patient's health and environment. Attention of the readers has been directed to utilize bioactive glasses as antibacterial agents for PEO coatings. Bioactive glasses are well known for their excellent bioactivity, biocompatibility, and antibacterial character. PEO coatings incorporated with bioactive glasses can provide environment-friendly antimicrobial surfaces with exceptional bioactivity, biocompatibility, and osseointegration. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 590-605, 2018.
等离子体电解氧化（PEO）是一种先进的技术，用于在轻金属上开发多孔氧化层，主要是为了提高耐腐蚀性和耐磨性。通过掺入几种离子和颗粒，氧化层还可以提供多种机械、生物医学、摩擦学和抗菌性能。由于生物医学植入物对抗菌表面的需求不断增加，已经通过掺入抗菌剂来开发抗菌 PEO 涂层。据报道，最广泛用作抗菌剂的金属纳米粒子对健康和环境构成严重威胁。为了克服这些涂层的当前局限性，非常需要开发对患者健康和环境无害的抗菌表面。读者已经注意到将生物活性玻璃用作 PEO 涂层的抗菌剂。生物活性玻璃以其优异的生物活性、生物相容性和抗菌特性而闻名。掺入生物活性玻璃的 PEO 涂层可以提供环保型抗菌表面，具有出色的生物活性、生物相容性和骨整合性。© 2017 威利父子公司。J 生物医学材料研究部分 A：106A：590-605，2018 年。
