College of Medical Veterinary and Life Sciences, Institute of Mental Health and Wellbeing, University of Glasgow, Glasgow, UK.
College of Medical Veterinary and Life Sciences, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Obes Rev. 2018 Jan;19(1):1-13. doi: 10.1111/obr.12593. Epub 2017 Oct 4.
This systematic review synthesized the available evidence on the effect of short-term periods of intermittent energy restriction (weekly intermittent energy restriction; ≥7-d energy restriction) in comparison with usual care (daily continuous energy restriction), in the treatment of overweight and obesity in adults. Six electronic databases were searched from inception to October 2016. Only randomized controlled trials of interventions (≥12 weeks) in adults with overweight and obesity were included. Five studies were included in this review. Weekly intermittent energy restriction periods ranged from an energy intake between 1757 and 6276 kJ/d . The mean duration of the interventions was 26 (range 14 to 48) weeks. Meta-analysis demonstrated no significant difference in weight loss between weekly intermittent energy restriction and continuous energy restriction post-intervention (weighted mean difference: -1.36 [-3.23, 0.51], p = 0.15) and at follow-up (weighted mean difference: -0.82 [-3.76, 2.11], p = 0.58). Both interventions achieved comparable weight loss of >5 kg and therefore were associated with clinical benefits to health. The findings support the use of weekly intermittent energy restriction as an alternative option for the treatment of obesity. Currently, there is insufficient evidence to support the long-term sustainable effects of weekly intermittent energy restriction on weight management.
本系统评价综合了现有关于短期间歇性能量限制（每周间歇性能量限制；≥7 天能量限制）与常规护理（每日连续能量限制）在治疗超重和肥胖成人方面的效果的证据。从创建到 2016 年 10 月，我们检索了 6 个电子数据库。仅纳入了超重和肥胖成年人的干预措施（≥12 周）的随机对照试验。本综述纳入了 5 项研究。每周间歇性能量限制期的能量摄入量介于 1757 至 6276kJ/d 之间。干预措施的平均持续时间为 26 周（范围 14 至 48 周）。荟萃分析显示，干预后（加权均数差：-1.36[-3.23, 0.51]，p=0.15）和随访时（加权均数差：-0.82[-3.76, 2.11]，p=0.58），每周间歇性能量限制与连续能量限制之间的体重减轻无显著差异。两种干预措施都实现了超过 5kg 的可比体重减轻，因此对健康具有临床益处。这些发现支持将每周间歇性能量限制作为肥胖治疗的替代方案。目前，尚无足够证据支持每周间歇性能量限制对体重管理的长期可持续效果。
