硬膜下注入溶栓剂治疗复发性硬膜下血肿
Subdural Instillation of a Thrombolytic Agent for Treatment of Recurrent Subdural Hematoma.
作者信息
Frenkel Mark B, Sarwal Aarti, Wren Mary Petrulis, Newey Christopher R, Couture Daniel E
机构信息
Departments of *Neurosurgery, †Neurology, ‡Anesthesiology (Section on Critical Care Medicine), §Wake Forest School of Medicine, Winston-Salem, NC; and ∥Department of Neurology, School of Medicine, University of Missouri Health, Columbia, MO.
出版信息
Clin Neuropharmacol. 2017 Nov/Dec;40(6):279-280. doi: 10.1097/WNF.0000000000000247.
OBJECTIVE
This study aims to report the case of a patient with recurrent subdural hemorrhage (SDH) who was administered tissue plasminogen activator through a subdural drain to enhance drainage and prevent recurrence.
METHODS
An 85-year-old man was treated for subacute over chronic SDH that kept on reaccumulating despite serial twist drill drainage, burr hole drainage, and craniotomy. No coagulopathy was identified with adequate blood pressure control.
RESULTS
Treatment with tissue plasminogen activator resulted in successful drainage of the SDH, and the patient had no further recurrence at 9-month follow-up.
目的
本研究旨在报告一例复发性硬膜下血肿（SDH）患者的病例，该患者通过硬膜下引流管给予组织型纤溶酶原激活剂以增强引流并预防复发。
方法
一名85岁男性因亚急性慢性硬膜下血肿接受治疗，尽管进行了多次钻孔引流、骨孔引流和开颅手术，但血肿仍不断重新积聚。在血压得到充分控制的情况下未发现凝血功能障碍。
结果
使用组织型纤溶酶原激活剂治疗成功引流了硬膜下血肿，患者在9个月的随访中未再复发。
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