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薄膜高能电流 X 射线探测器的门控 MV 成像:一项蒙特卡罗研究。

Portal MV imaging with thin-film high-energy current X-ray detectors: A Monte Carlo study.

机构信息

Department of Physics and Applied Physics, Medical Physics Program, University of Massachusetts Lowell, Lowell, MA, USA.

Harvard Medical School, Dana Farber Cancer Institute, Brigham and Women's Hospital, Boston, MA, USA.

出版信息

Med Phys. 2017 Dec;44(12):6128-6137. doi: 10.1002/mp.12613. Epub 2017 Oct 28.

Abstract

PURPOSE

We investigate the potential of the recently introduced high-energy current (HEC) thin-film detector as an alternative design to existing electronic portal imaging devices (EPID). The HEC radiation detectors employ multiple nano-/micrometer layers made of disparate atomic number (Z) conductors separated by solid or gaseous (e.g., air) dielectrics. The HEC detector may be designed as an external structure or an auxiliary device integrated into the existing EPID.

METHOD

Using Geant4 Monte Carlo simulations, we compare the image contrast of a HEC detector to that of a commercial EPID device (AS500) for a 2.5 MV X-ray beam. The detector response was modeled using a series of monoenergetic incident photons with detector signal scored as the energy deposition in the air gaps (HEC) and in the phosphor layer (EPID). Las Vegas (LV) phantom was employed to test the spatial resolution and contrast of the single- and multielement HEC detector. The HEC detector pixel size was the same as for AS500 (0.78 mm × 0.78 mm). In addition, image contrast of a water/bone phantom using both the multielement HEC and EPID detectors was simulated and compared.

RESULTS

The HEC detector has higher relative response to low-energy photons compared to EPID. The multielement HEC has 32.3 times greater response at 100 keV than at 500 keV, while the EPID without copper plate shows a factor of 6.8 between the same energies. LV phantom images indicate that the image contrast is approximately the same for single- and multielement HEC detectors, but the latter has lower noise. Both single- and multielement HEC could resolve a 2 mm diameter hole with an image magnification factor of 1.2. In the present design, the HEC detector has much less material (9.66 mg/cm gold) compared to EPID (133 mg/cm Gd O S) to interact with incident photons. For imaging bony structures, the HEC detector needs about nine times greater photon flux as the EPID to acquire data at same uncertainty level. Despite this, the HEC sensor requires less than 1 cGy dose to obtain images with statistical uncertainty better than 2.5%. In the case when the field diameter is 10 cm, the multielement HEC image contrast is 14.3% higher than that of EPID with copper removed. When the field diameter is decreased to 5 cm, HEC contrast is 27.1% better than the EPID contrast.

CONCLUSION

It is demonstrated that the image contrast of HEC detectors are comparable and in some cases better than that of the standard EPID design. This opens a potential for complementary HEC and EPID designs that may better utilize the kV portion of the spectrum.

摘要

目的

我们研究了最近引入的高能电流(HEC)薄膜探测器作为现有电子射野影像设备(EPID)替代设计的潜力。HEC 辐射探测器采用由不同原子数(Z)导体组成的多层纳米/微米层,这些导体由固体或气体(例如空气)电介质隔开。HEC 探测器可以设计为外部结构或集成到现有 EPID 中的辅助设备。

方法

使用 Geant4 蒙特卡罗模拟,我们比较了 HEC 探测器与商业 EPID 设备(AS500)对 2.5MV X 射线束的图像对比度。使用一系列单能入射光子对探测器响应进行建模,探测器信号被记录为在气隙(HEC)和磷光体层(EPID)中的能量沉积。拉斯维加斯(LV)体模用于测试单元和多元 HEC 探测器的空间分辨率和对比度。HEC 探测器的像素尺寸与 AS500 相同(0.78mm×0.78mm)。此外,还模拟并比较了使用多元素 HEC 和 EPID 探测器的水/骨体模的图像对比度。

结果

与 EPID 相比,HEC 探测器对低能光子的相对响应更高。多元素 HEC 在 100keV 时的响应比在 500keV 时高 32.3 倍,而没有铜板的 EPID 在相同能量下的响应为 6.8 倍。LV 体模图像表明,单元和多元 HEC 的图像对比度大致相同,但后者噪声更低。单元和多元 HEC 都可以分辨出直径为 2 毫米的孔,图像放大倍数为 1.2。在本设计中,与 EPID(133mg/cm GdO S)相比,HEC 探测器与入射光子相互作用的材料(9.66mg/cm 金)要少得多。对于成像骨结构,HEC 探测器需要大约九倍于 EPID 的光子通量才能在相同的不确定度水平下获取数据。尽管如此,HEC 传感器仅需小于 1cGy 的剂量即可获得具有低于 2.5%统计不确定性的图像。当照射野直径为 10cm 时,多元 HEC 的图像对比度比去除铜板的 EPID 高 14.3%。当照射野直径减小到 5cm 时,HEC 的对比度比 EPID 的对比度好 27.1%。

结论

证明了 HEC 探测器的图像对比度与标准 EPID 设计相当,在某些情况下甚至更好。这为 HEC 和 EPID 的互补设计开辟了可能性,这些设计可能更好地利用光谱的千伏部分。

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