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使用Geant4蒙特卡罗模拟研究医用加速器中用于射野成像的外部铝靶的应用。

Investigation of the use of external aluminium targets for portal imaging in a medical accelerator using Geant4 Monte Carlo simulation.

作者信息

Kim Hyungdong, Kim Byungyong, Baek Jonggeun, Oh Youngkee, Yun Sangmo, Jang Hyunsoo

机构信息

1 Department of Radiation Oncology, Daegu Fatima Hospital , Daegu , South Korea.

2 Department of Radiation Oncology, Semyung Christianity Hospital , Pohang , South Korea.

出版信息

Br J Radiol. 2018 Apr;91(1084):20170376. doi: 10.1259/bjr.20170376. Epub 2018 Feb 6.

Abstract

OBJECTIVE

To install a low-Z target on the wedge tray mount of a medical linear accelerator to create a new image beam and to confirm image contrast enhancement.

METHODS

Experimental low-energy photon beams were produced with the linac running in the 6 MeV electron mode and with a low-Z target installed on the wedge tray mount [denoted 6 MeV (low-Z target)]. Geant4 Monte Carlo simulation was performed to analyse the energy spectrum and image contrast of a 6 MeV (low-Z target) beam. This study modelled the 6 MeV (low-Z target) beam and the 6 MV (megavoltage) radiotherapy photon beam and verified model validity by measurement. In addition, a contrast phantom was modelled to quantitatively compare the image contrasts of the 6 MeV (low-Z target) beam and the 6 MV radiotherapy photon beam. A low-Z target was fabricated to generate low-energy photons (25-150 keV) from incident electrons, and a portal image of the Alderson RANDO phantom was acquired using a clinical linear accelerator for qualitative analysis.

RESULTS

The measured and calculated percentage depth dose of the 6 MV photon and 6 MeV (Al) beams were consistent within 1.5 and 1.6%, respectively, and calculated lateral profiles of the 6 MV photon beam and the 6 MeV (Al) beam were consistent with the measured results within 1.5 and 1.9%, respectively. Although low-energy photons (25-150 keV) of the 6 MV photon beam were only 0.3%, the Be, C, and Al low-Z targets, but not the Ti target, generated 34.4 to 38.5% low-energy photons. In 5 to 20 cm water phantoms, contrast of the 6 MeV (Al) beam was approximately 1.16 times greater than that of the 6 MV beam. The contrasts of 6 MeV (Al) and 6 MV photon beams in the 20 cm water phantom were ~34% lower than those in the 5 cm water phantom. 6 MeV (Al)/CR (computed radiography) images of the human body phantom were more vivid and detailed than 6 MV/EPID (electronic portal imaging device) and 6 MeV (Al)/EPID images.

CONCLUSION

The experimental beam with a low-Z target, which was simply installed on the wedge tray mount of the radiotherapy linear accelerator, generated significantly more low-energy photons than the 6 MV radiotherapy photon beam, and provided better quality portal images. Advances in knowledge: This study shows that, unlike the existing low-Z beam studies, a low-Z target can be installed outside the head of a linear accelerator to improve portal image quality.

摘要

目的

在医用直线加速器的楔形托盘支架上安装低原子序数靶,以产生新的成像束并确认图像对比度增强。

方法

直线加速器运行在6兆电子伏电子模式且在楔形托盘支架上安装低原子序数靶时产生实验性低能光子束[表示为6兆电子伏(低原子序数靶)]。进行Geant4蒙特卡罗模拟以分析6兆电子伏(低原子序数靶)束的能谱和图像对比度。本研究对6兆电子伏(低原子序数靶)束和6兆伏(兆伏级)放射治疗光子束进行建模,并通过测量验证模型有效性。此外,对一个对比度体模进行建模,以定量比较6兆电子伏(低原子序数靶)束和6兆伏放射治疗光子束的图像对比度。制作了一个低原子序数靶,用于从入射电子产生低能光子(25 - 150千电子伏),并使用临床直线加速器获取Alderson RANDO体模的射野图像进行定性分析。

结果

6兆伏光子束和6兆电子伏(铝)束的测量和计算深度剂量百分比分别在1.5%和1.6%以内一致,6兆伏光子束和6兆电子伏(铝)束的计算横向轮廓与测量结果分别在1.5%和1.9%以内一致。尽管6兆伏光子束的低能光子(25 - 150千电子伏)仅为0.3%,但铍、碳和铝低原子序数靶,而非钛靶,产生了34.4%至38.5%的低能光子。在5至20厘米水模中,6兆电子伏(铝)束的对比度约为6兆伏束的1.16倍。20厘米水模中6兆电子伏(铝)和6兆伏光子束的对比度比5厘米水模中的低约34%。人体体模的6兆电子伏(铝)/计算机X线摄影(CR)图像比6兆伏/电子射野成像装置(EPID)和6兆电子伏(铝)/EPID图像更生动、更详细。

结论

在放射治疗直线加速器的楔形托盘支架上简单安装低原子序数靶的实验束,产生的低能光子比6兆伏放射治疗光子束显著更多,并提供了质量更好的射野图像。知识进展:本研究表明,与现有的低原子序数束研究不同,低原子序数靶可安装在线性加速器头部外部以提高射野图像质量。

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