Chen Jian Dz, Lin Zhiyue, McCALLUM Richard W
Institute for Healthcare Research, Oklahoma City, OklahomaDepartment of Medicine, The University of Kansas Medical Center, Kansas City, Kansas, USA.
J Gastroenterol Hepatol. 1998 Nov;13(S3):S232-S236. doi: 10.1111/j.1440-1746.1998.tb01883.x.
As in the heart, there is a pacemaker in the human stomach and it generates myoelectrical activity with a frequency of approximately three cycles per minute. Abnormalities in gastric myoelectrical activity may result in gastric motility disorders, such as gastroparesis. Electrical stimulation of the stomach is achieved by delivering electrical currents via electrodes attached to the smooth muscle of the stomach. Recently, a number of studies on electrical stimulation of the stomach in both humans and dogs have indicated that gastric electrical stimulation with appropriate parameters is able to entrain gastric slow waves and normalize gastric dysrhythmias. This has led some investigators to use gastric electrical stimulation to treat patients with gastroparesis. Previous studies and the current state of the field in gastric electrical stimulation in treatment of gastroparesis will be discussed and summarized.
与心脏一样，人的胃中也有一个起搏器，它以每分钟约三个周期的频率产生肌电活动。胃肌电活动异常可能导致胃动力障碍，如胃轻瘫。通过连接到胃平滑肌的电极输送电流来实现对胃的电刺激。最近，一些关于人和狗胃电刺激的研究表明，具有适当参数的胃电刺激能够带动胃慢波并使胃心律失常正常化。这使得一些研究人员使用胃电刺激来治疗胃轻瘫患者。将对胃电刺激治疗胃轻瘫的先前研究和该领域的现状进行讨论和总结。
