冠状动脉旁路移植术患者淋巴细胞与单核细胞比值与大隐静脉移植血管通畅性的关系
The relationship between lymphocyte-to-monocyte ratio and saphenous vein graft patency in patients with coronary artery bypass graft.
作者信息
Oksuz Fatih, Elcik Deniz, Yarlioglues Mikail, Duran Mustafa, Ozturk Selcuk, Celik Ibrahim Etem, Kurtul Alparslan, Kilic Alparslan, Murat Sani Namik
机构信息
Ankara Education & Research Hospital, Department of Cardiology, Ankara, Turkey.
出版信息
Biomark Med. 2017 Oct;11(10):867-876. doi: 10.2217/bmm-2017-0079. Epub 2017 Oct 4.
AIM
A lower lymphocyte count and a high monocyte count give important clues about the prognosis of various cardiovascular diseases. We hypothesized that lymphocyte-to-monocyte ratio (LMR) was associated with the saphenous vein graft disease (SVGD) in patients with coronary artery bypass graft (CABG).
PATIENTS & METHODS: A total of 218 patients with previous history of CABG surgery, who underwent coronary angiography due to stable angina symptoms, were investigated, retrospectively.
RESULTS
LMR levels were significantly lower in the SVGD group. Multiple logistic regression analyses showed that LMR levels were independent predictors of SVGD (OR: 0.648; 95% CI: 0.469-0.894; p = 0.008).
CONCLUSION
Our results suggested that LMR levels may provide useful information for the relevant risk evaluation of SVGD in CABG patients.
目的
较低的淋巴细胞计数和较高的单核细胞计数为各种心血管疾病的预后提供了重要线索。我们假设淋巴细胞与单核细胞比值（LMR）与冠状动脉旁路移植术（CABG）患者的大隐静脉移植血管疾病（SVGD）相关。
患者与方法
对218例有CABG手术史、因稳定型心绞痛症状接受冠状动脉造影的患者进行回顾性研究。
结果
SVGD组的LMR水平显著较低。多因素logistic回归分析显示，LMR水平是SVGD的独立预测因素（OR：0.648；95%CI：0.469-0.894；p = 0.008）。
结论
我们的结果表明，LMR水平可能为CABG患者SVGD的相关风险评估提供有用信息。
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