Roncali Emilie, Mosleh-Shirazi Mohammad Amin, Badano Aldo
Department of Biomedical Engineering, University of California Davis, Davis, CA, United States of America.
Phys Med Biol. 2017 Oct 4;62(20):R207-R235. doi: 10.1088/1361-6560/aa8b31.
Computational modelling of radiation transport can enhance the understanding of the relative importance of individual processes involved in imaging systems. Modelling is a powerful tool for improving detector designs in ways that are impractical or impossible to achieve through experimental measurements. Modelling of light transport in scintillation detectors used in radiology and radiotherapy imaging that rely on the detection of visible light plays an increasingly important role in detector design. Historically, researchers have invested heavily in modelling the transport of ionizing radiation while light transport is often ignored or coarsely modelled. Due to the complexity of existing light transport simulation tools and the breadth of custom codes developed by users, light transport studies are seldom fully exploited and have not reached their full potential. This topical review aims at providing an overview of the methods employed in freely available and other described optical Monte Carlo packages and analytical models and discussing their respective advantages and limitations. In particular, applications of optical transport modelling in nuclear medicine, diagnostic and radiotherapy imaging are described. A discussion on the evolution of these modelling tools into future developments and applications is presented.
辐射传输的计算建模可以增进对成像系统中各个过程相对重要性的理解。建模是一种强大的工具,能够以实验测量无法实现或不切实际的方式改进探测器设计。在放射学和放射治疗成像中使用的闪烁探测器中,依赖于可见光检测的光传输建模在探测器设计中发挥着越来越重要的作用。从历史上看,研究人员在电离辐射传输建模方面投入了大量精力,而光传输往往被忽视或进行粗略建模。由于现有光传输模拟工具的复杂性以及用户开发的自定义代码的广度,光传输研究很少得到充分利用,尚未发挥其全部潜力。本专题综述旨在概述免费可用的以及其他所述光学蒙特卡罗软件包和分析模型中采用的方法,并讨论它们各自的优缺点。特别介绍了光传输建模在核医学、诊断和放射治疗成像中的应用。还讨论了这些建模工具在未来发展和应用中的演变。