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验证用于放射性能量范围内光子剂量测量的塑料闪烁探测器。

Validating plastic scintillation detectors for photon dosimetry in the radiologic energy range.

机构信息

Département de physique, de génie physique et d'optique, Université Laval, Québec, Québec, Canada.

出版信息

Med Phys. 2012 Sep;39(9):5308-16. doi: 10.1118/1.4738964.

Abstract

PURPOSE

Photon dosimetry in the kilovolt (kV) energy range represents a major challenge for diagnostic and interventional radiology and superficial therapy. Plastic scintillation detectors (PSDs) are potentially good candidates for this task. This study proposes a simple way to obtain accurate correction factors to compensate for the response of PSDs to photon energies between 80 and 150 kVp. The performance of PSDs is also investigated to determine their potential usefulness in the diagnostic energy range.

METHODS

A 1-mm-diameter, 10-mm-long PSD was irradiated by a Therapax SXT 150 unit using five different beam qualities made of tube potentials ranging from 80 to 150 kVp and filtration thickness ranging from 0.8 to 0.2 mmAl + 1.0 mmCu. The light emitted by the detector was collected using an 8-m-long optical fiber and a polychromatic photodiode, which converted the scintillation photons to an electrical current. The PSD response was compared with the reference free air dose rate measured with a calibrated Farmer NE2571 ionization chamber. PSD measurements were corrected using spectra-weighted corrections, accounting for mass energy-absorption coefficient differences between the sensitive volumes of the ionization chamber and the PSD, as suggested by large cavity theory (LCT). Beam spectra were obtained from x-ray simulation software and validated experimentally using a CdTe spectrometer. Correction factors were also obtained using Monte Carlo (MC) simulations. Percent depth dose (PDD) measurements were compensated for beam hardening using the LCT correction method. These PDD measurements were compared with uncorrected PSD data, PDD measurements obtained using Gafchromic films, Monte Carlo simulations, and previous data.

RESULTS

For each beam quality used, the authors observed an increase of the energy response with effective energy when no correction was applied to the PSD response. Using the LCT correction, the PSD response was almost energy independent, with a residual 2.1% coefficient of variation (COV) over the 80-150-kVp energy range. Monte Carlo corrections reduced the COV to 1.4% over this energy range. All PDD measurements were in good agreement with one another except for the uncorrected PSD data, in which an over-response was observed with depth (13% at 10 cm with a 100 kVp beam), showing that beam hardening had a non-negligible effect on the PSD response. A correction based on LCT compensated very well for this effect, reducing the over-response to 3%.

CONCLUSION

In the diagnostic energy range, PSDs show high-energy dependence, which can be corrected using spectra-weighted mass energy-absorption coefficients, showing no considerable sign of quenching between these energies. Correction factors obtained by Monte Carlo simulations confirm that the approximations made by LCT corrections are valid. Thus, PSDs could be useful for real-time dosimetry in radiology applications.

摘要

目的

在千伏 (kV) 能量范围内的光子剂量学对诊断和介入放射学以及浅表治疗来说是一个主要挑战。塑料闪烁探测器 (PSD) 是这项任务的潜在良好候选者。本研究提出了一种简单的方法来获得准确的校正因子,以补偿 PSD 对 80 至 150 kVp 光子能量的响应。还研究了 PSD 的性能,以确定它们在诊断能量范围内的潜在有用性。

方法

使用 Therapax SXT 150 装置照射直径为 1 毫米、长 10 毫米的 PSD,使用管电压范围为 80 至 150 kVp 且过滤厚度范围为 0.8 至 0.2 毫米 Al + 1.0 毫米 Cu 的五种不同射线束质量。探测器发出的光通过 8 米长的光纤和多色光电二极管收集,将闪烁光子转换为电流。将 PSD 响应与使用校准的 Farmer NE2571 电离室测量的参考自由空气剂量率进行比较。使用大空腔理论 (LCT) 建议的光谱加权校正来校正 PSD 测量值,以补偿电离室和 PSD 的敏感体积之间的质量能量吸收系数差异。使用 X 射线模拟软件获得束谱,并使用 CdTe 光谱仪进行实验验证。还使用蒙特卡罗 (MC) 模拟获得校正因子。使用 LCT 校正方法补偿束硬化对百分深度剂量 (PDD) 测量的影响。将这些 PDD 测量值与未校正的 PSD 数据、使用 Gafchromic 胶片获得的 PDD 测量值、蒙特卡罗模拟和以前的数据进行比较。

结果

对于使用的每种射束质量,当不对 PSD 响应进行校正时,作者观察到能量响应随有效能量的增加而增加。使用 LCT 校正后,PSD 响应几乎与能量无关,在 80-150 kVp 能量范围内的剩余变异系数 (COV) 为 2.1%。在这个能量范围内,MC 校正将 COV 降低到 1.4%。除了未校正的 PSD 数据外,所有 PDD 测量值都非常吻合,在未校正的 PSD 数据中,在深度处观察到响应过度(100 kVp 束时在 10 cm 处为 13%),表明束硬化对 PSD 响应有不可忽略的影响。基于 LCT 的校正很好地补偿了这种影响,将过响应降低到 3%。

结论

在诊断能量范围内,PSD 表现出高能量依赖性,可使用光谱加权质量能量吸收系数进行校正,在这些能量之间没有明显的淬灭迹象。通过蒙特卡罗模拟获得的校正因子证实了 LCT 校正的近似值是有效的。因此,PSD 可用于放射学应用中的实时剂量学。

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