轻度认知障碍老年人的功能衰退：阿尔茨海默病协作研究日常生活能力量表的文化适应性
Functional decline in the elderly with MCI: Cultural adaptation of the ADCS-ADL scale.
作者信息
Cintra Fabiana Carla Matos da Cunha, Cintra Marco Túlio Gualberto, Nicolato Rodrigo, Bertola Laiss, Ávila Rafaela Teixeira, Malloy-Diniz Leandro Fernandes, Moraes Edgar Nunes, Bicalho Maria Aparecida Camargos
机构信息
Occupational Therapist and MSc in Neuroscience from Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
PhD, MD, Geriatrician at Instituto Jenny de Andrade Faria de Atenção à Saúde do Idoso, Hospital das Clínicas (HC) da UFMG, and MSc in Sciences applied to Adult Health from UFMG, Belo Horizonte, MG, Brazil.
出版信息
Rev Assoc Med Bras (1992). 2017 Jul;63(7):590-599. doi: 10.1590/1806-9282.63.07.590.
OBJECTIVE
Translate, transcultural adaptation and application to Brazilian Portuguese of the Alzheimer's Disease Cooperative Study - Activities of Daily Living (ADCS-ADL) scale as a cognitive screening instrument.
METHOD
We applied the back translation added with pretest and bilingual methods. The sample was composed by 95 elderly individuals and their caregivers. Thirty-two (32) participants were diagnosed as mild cognitive impairment (MCI) patients, 33 as Alzheimer's disease (AD) patients and 30 were considered as cognitively normal individuals.
RESULTS
There were only little changes on the scale. The Cronbach alpha coefficient was 0.89. The scores were 72.9 for control group, followed by MCI (65.1) and by AD (55.9), with a p-value < 0.001. The ROC curve value was 0.89. We considered a cut point of 72 and we observed a sensibility of 86.2%, specificity of 70%, positive predictive value of 86.2%, negative predictive value of 70%, positive likelihood ratio of 2.9 and negative likelihood ratio of 0.2.
CONCLUSION
ADCS-ADL scale presents satisfactory psychometric properties to discriminate between MCI, AD and normal cognition.
目的
将阿尔茨海默病协作研究日常生活活动（ADCS-ADL）量表作为一种认知筛查工具进行翻译、跨文化调适并应用于巴西葡萄牙语。
方法
我们采用了回译并辅以预测试和双语方法。样本由95名老年人及其照料者组成。32名参与者被诊断为轻度认知障碍（MCI）患者，33名被诊断为阿尔茨海默病（AD）患者，30名被视为认知正常个体。
结果
该量表仅有微小变化。克朗巴哈α系数为0.89。对照组得分72.9，其次是MCI组（65.1）和AD组（55.9），p值<0.001。ROC曲线值为0.89。我们设定切点为72，观察到敏感度为86.2%，特异度为70%，阳性预测值为86.2%，阴性预测值为70%，阳性似然比为2.9，阴性似然比为0.2。
结论
ADCS-ADL量表具有令人满意的心理测量学特性，可用于区分MCI、AD和正常认知。
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