Hashimoto Takeshi, Yoshioka Kunihiko, Gondo Tatsuo, Hasama Kazuki, Hirasawa Yosuke, Nakashima Jun, Tachibana Masaaki, Ohno Yoshio
1 Department of Urology, Tokyo Medical University , Tokyo, Japan .
2 Institute for Urology , Shin-yurigaoka General Hospital, Kawasaki, Japan .
J Endourol. 2018 Jan;32(1):40-45. doi: 10.1089/end.2017.0459. Epub 2017 Nov 3.
Urinary incontinence is one of the most bothersome adversities after robot-assisted radical prostatectomy (RARP). The aim of this study was to investigate the urinary continence recovery and the effect of various surgical techniques.
We previously reported that posterior rhabdosphincter reconstruction and nerve-sparing were independent predictors of urinary continence recovery 1 month after catheter removal in 199 patients who underwent RARP. Retrospectively, we further reviewed those 199 patients for urinary continence recovery at 3 months or later after RARP. The relationships of urinary continence with perioperative findings, including surgical procedures, were evaluated at 3 to 12 months after RARP. The Fisher exact test and Mann-Whitney rank sum test were used for evaluating variables between the groups. Multivariate logistic regression analysis was performed to investigate the association between urinary continence and perioperative factors.
On univariate analyses, surgeon experience, lateral bladder neck preservation (BNP), anterior reconstruction, and posterior reconstruction were significantly associated with urinary continence recovery 3 months after RARP, but only lateral BNP was independently associated with urinary continence recovery in a multivariate analysis. Similarly, on univariate analyses, surgeon experience, lateral BNP, and posterior reconstruction were significantly associated with continence recovery at 6 months or later after surgery. However, multivariate analyses showed that only lateral BNP was significantly associated with urinary continence recovery 6 months or later after surgery.
Although the lateral BNP technique did not affect immediate urinary continence recovery, this procedure was significantly associated with continence recovery 3 months or later after RARP.
尿失禁是机器人辅助根治性前列腺切除术(RARP)后最恼人的并发症之一。本研究旨在调查尿失禁的恢复情况以及各种手术技术的效果。
我们之前报道过,在199例行RARP的患者中,后尿道括约肌重建和保留神经是拔除导尿管后1个月尿失禁恢复的独立预测因素。我们对这199例患者进行回顾性研究,进一步评估RARP术后3个月或更晚时间的尿失禁恢复情况。在RARP术后3至12个月评估尿失禁与围手术期结果(包括手术方式)之间的关系。采用Fisher确切检验和Mann-Whitney秩和检验评估组间变量。进行多因素logistic回归分析以研究尿失禁与围手术期因素之间的关联。
单因素分析显示,术者经验、保留膀胱颈外侧(BNP)、前部重建和后部重建与RARP术后3个月尿失禁恢复显著相关,但多因素分析中只有保留膀胱颈外侧与尿失禁恢复独立相关。同样,单因素分析显示,术者经验、保留膀胱颈外侧和后部重建与术后6个月或更晚的尿失禁恢复显著相关。然而,多因素分析显示,只有保留膀胱颈外侧与RARP术后6个月或更晚的尿失禁恢复显著相关。
虽然保留膀胱颈外侧技术不影响早期尿失禁恢复,但该手术与RARP术后3个月或更晚的尿失禁恢复显著相关。