• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The sigma receptor: a novel site implicated in psychosis and antipsychotic drug efficacy.

作者信息

Deutsch S I, Weizman A, Goldman M E, Morihisa J M

机构信息

Department of Psychiatry, Georgetown University School of Medicine, Washington, D.C.

出版信息

Clin Neuropharmacol. 1988 Apr;11(2):105-19.

PMID:2897876
Abstract
摘要

相似文献

1
The sigma receptor: a novel site implicated in psychosis and antipsychotic drug efficacy.西格玛受体：一个与精神病及抗精神病药物疗效相关的新位点。
Clin Neuropharmacol. 1988 Apr;11(2):105-19.
2
5-HT6 receptor ligands and their antipsychotic potential.5-羟色胺6受体配体及其抗精神病潜力。
Int Rev Neurobiol. 2011;96:141-61. doi: 10.1016/B978-0-12-385902-0.00006-1.
3
Pilot studies on the effect of SL 82.0715 in psychotic syndromes.关于SL 82.0715对精神病综合征影响的初步研究。
Clin Neuropharmacol. 1992;15 Suppl 1 Pt A:699A-700A. doi: 10.1097/00002826-199201001-00361.
4
Quantification of neuroreceptors in living human brain. v. endogenous neurotransmitter inhibition of haloperidol binding in psychosis.活体人类大脑中神经受体的定量分析。第五部分：精神病中内源性神经递质对氟哌啶醇结合的抑制作用。
J Cereb Blood Flow Metab. 2001 Aug;21(8):982-94. doi: 10.1097/00004647-200108000-00011.
5
Neuroleptic drugs and the sigma receptor.
Am J Psychiatry. 1990 Aug;147(8):1093-4. doi: 10.1176/ajp.147.8.1093.
6
[Specific binding of N-allylnormetazocine (SKF 10047), a ligand of sigma-opioid receptors, with liver membranes].
Bioorg Khim. 1985 Oct;11(10):1380-4.
7
Delineating biochemical and functional properties of sigma receptors: emerging concepts.阐明σ受体的生化和功能特性：新出现的概念
Crit Rev Neurobiol. 1993;7(3-4):187-203.
8
[Neuropharmacological effects of sigma receptor ligands: anxiolytic, anti-amnesic and neuroprotective effects].σ受体配体的神经药理学效应：抗焦虑、抗遗忘和神经保护作用
Nihon Shinkei Seishin Yakurigaku Zasshi. 1996 Jun;16(3):73-84.
9
(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties.（+）-顺式-N-乙烯氨基-N-去甲美沙酮衍生物。具有拮抗剂特性的新型选择性σ配体。
J Med Chem. 1998 May 7;41(10):1574-80. doi: 10.1021/jm970333f.
10
The sigma enigma: biochemical and functional correlates emerge for the haloperidol-sensitive sigma binding site.西格玛之谜：针对氟哌啶醇敏感的西格玛结合位点，出现了生化与功能相关性。
Trends Pharmacol Sci. 1990 Jun;11(6):213-5. doi: 10.1016/0165-6147(90)90241-y.

引用本文的文献

1
Evaluation of [F]F-TZ3108 for PET Imaging of Metabolic-Associated Fatty Liver Disease.评估 [F]F-TZ3108 用于代谢相关脂肪性肝病的 PET 成像。
Mol Imaging Biol. 2022 Dec;24(6):909-919. doi: 10.1007/s11307-022-01740-2. Epub 2022 Jun 15.
2
Synthesis and in vitro biological evaluation of carbonyl group-containing analogues for σ1 receptors.含羰基 σ1 受体类似物的合成及体外生物学评价。
J Med Chem. 2011 Aug 11;54(15):5362-72. doi: 10.1021/jm200203f. Epub 2011 Jul 20.
3
Characterization of phenothiazine-induced apoptosis in neuroblastoma and glioma cell lines: clinical relevance and possible application for brain-derived tumors.
吩噻嗪诱导神经母细胞瘤和胶质瘤细胞系凋亡的特征：临床相关性及对脑源性肿瘤的可能应用
J Mol Neurosci. 2004;22(3):189-98. doi: 10.1385/JMN:22:3:189.
4
Evaluation of the neurotoxic activity of typical and atypical neuroleptics: relevance to iatrogenic extrapyramidal symptoms.典型和非典型抗精神病药物的神经毒性活性评估：与医源性锥体外系症状的相关性
Cell Mol Neurobiol. 2001 Dec;21(6):705-16. doi: 10.1023/a:1015152021192.
5
Blockade by sigma site ligands of high voltage-activated Ca2+ channels in rat and mouse cultured hippocampal pyramidal neurones.大鼠和小鼠培养海马锥体神经元中σ位点配体对高电压激活的Ca2+通道的阻断作用。
Br J Pharmacol. 1995 Dec;116(7):2801-10. doi: 10.1111/j.1476-5381.1995.tb15929.x.
6
Current hypotheses on sigma receptors and their physiological role: possible implications in psychiatry.关于西格玛受体及其生理作用的当前假说：对精神病学的可能影响。
J Psychiatry Neurosci. 1993 Jul;18(4):157-72.
7
Focal stimulation of specific pathways in the rat hippocampus causes a reduction in radioligand binding to the haloperidol-sensitive sigma receptor.
Exp Brain Res. 1991;85(3):528-36. doi: 10.1007/BF00231736.
8
Discriminative stimulus effects of spiradoline, a kappa-opioid agonist.κ-阿片受体激动剂spiradoline的辨别性刺激效应
Psychopharmacology (Berl). 1991;105(4):447-52. doi: 10.1007/BF02244362.
9
Effects of NMDA receptor antagonists and sigma ligands on the acquisition of conditioned fear in mice.
Psychopharmacology (Berl). 1991;104(1):27-34. doi: 10.1007/BF02244550.
10
Peripheral markers of neurochemical function among workers exposed to styrene.接触苯乙烯工人神经化学功能的外周标志物
Br J Ind Med. 1992 Aug;49(8):560-5. doi: 10.1136/oem.49.8.560.