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脂质与碳水化合物代谢于…… (你提供的原文不完整,后面应该还有具体内容)

Lipid and Carbohydrate Metabolism in .

作者信息

Watts Jennifer L, Ristow Michael

机构信息

School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164

Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach-Zurich, Switzerland.

出版信息

Genetics. 2017 Oct;207(2):413-446. doi: 10.1534/genetics.117.300106.

Abstract

Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.

摘要

脂质和碳水化合物代谢是高度保守的过程,几乎影响生物体生物学的各个方面。食用细菌,其由脂质、碳水化合物和蛋白质组成,在消化过程中分解为脂肪酸、单糖和氨基酸前体。利用这些营养物质,合成了发育和行为所需的多种代谢物。在本综述中,我们概述了已在[具体研究对象]中得到表征的脂质和碳水化合物结构以及生物合成和分解途径。我们关注使用突变菌株的功能研究,这些研究揭示了特定脂质和碳水化合物在发育、衰老以及适应不断变化的环境条件过程中的生理作用。

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本文引用的文献

1
Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation.
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2
Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan.
Nature. 2017 Apr 13;544(7649):185-190. doi: 10.1038/nature21686. Epub 2017 Apr 5.
3
An updated meta-analysis of cohort studies: Diabetes and risk of Alzheimer's disease.
Diabetes Res Clin Pract. 2017 Feb;124:41-47. doi: 10.1016/j.diabres.2016.10.024. Epub 2016 Nov 9.
4
Nutritional Programming of Lifespan by FOXO Inhibition on Sugar-Rich Diets.
Cell Rep. 2017 Jan 10;18(2):299-306. doi: 10.1016/j.celrep.2016.12.029.
6
Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.
J Lipid Res. 2017 Jan;58(1):72-80. doi: 10.1194/jlr.M069385. Epub 2016 Nov 24.
7
A Caenorhabditis elegans Model Elucidates a Conserved Role for TRPA1-Nrf Signaling in Reactive α-Dicarbonyl Detoxification.
Curr Biol. 2016 Nov 21;26(22):3014-3025. doi: 10.1016/j.cub.2016.09.024. Epub 2016 Oct 20.
8
Ribonuclease-Mediated Control of Body Fat.
Dev Cell. 2016 Nov 7;39(3):359-369. doi: 10.1016/j.devcel.2016.09.018. Epub 2016 Oct 13.
9
Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.
J Diet Suppl. 2017 May 4;14(3):264-277. doi: 10.1080/19390211.2016.1212959. Epub 2016 Sep 28.

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