Watts Jennifer L, Ristow Michael
School of Molecular Biosciences and Center for Reproductive Biology, Washington State University, Pullman, Washington 99164
Energy Metabolism Laboratory, Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute of Technology Zurich, 8603 Schwerzenbach-Zurich, Switzerland.
Genetics. 2017 Oct;207(2):413-446. doi: 10.1534/genetics.117.300106.
Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all aspects of organismal biology. eat bacteria, which consist of lipids, carbohydrates, and proteins that are broken down during digestion into fatty acids, simple sugars, and amino acid precursors. With these nutrients, synthesizes a wide range of metabolites that are required for development and behavior. In this review, we outline lipid and carbohydrate structures as well as biosynthesis and breakdown pathways that have been characterized in We bring attention to functional studies using mutant strains that reveal physiological roles for specific lipids and carbohydrates during development, aging, and adaptation to changing environmental conditions.
脂质和碳水化合物代谢是高度保守的过程,几乎影响生物体生物学的各个方面。食用细菌,其由脂质、碳水化合物和蛋白质组成,在消化过程中分解为脂肪酸、单糖和氨基酸前体。利用这些营养物质,合成了发育和行为所需的多种代谢物。在本综述中,我们概述了已在[具体研究对象]中得到表征的脂质和碳水化合物结构以及生物合成和分解途径。我们关注使用突变菌株的功能研究,这些研究揭示了特定脂质和碳水化合物在发育、衰老以及适应不断变化的环境条件过程中的生理作用。