Tarvade Sanjay, Lane Andrew S
Staff Specialist in Intensive Care Medicine, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Senior Lecturer in Intensive Care Medicine, Sydney Medical School, Sydney, NSW, Australia.
J Intensive Care Soc. 2015 May;16(2):172-178. doi: 10.1177/1751143714565855. Epub 2015 Jan 12.
Group A streptococcus (GAS) causes severe infections in obstetric patients. A rare complication is rapidly progressive necrotising myometritis. Postpartum necrotising myometritis has been previously described; however, antenatal development of such a condition is extremely rare. We present a patient who developed antenatal necrotising myometritis and toxic shock syndrome (TSS) due to GAS during the first trimester of pregnancy, eventually requiring hysterectomy and bilateral oophorectomy. We discuss the rare complication of ante-partum necrotising myometritis, as well as the antibiotic therapy, and treatment of TSS associated with severe Group A Streptococcal infections.
A组链球菌（GAS）可导致产科患者发生严重感染。一种罕见的并发症是快速进展性坏死性子宫肌炎。产后坏死性子宫肌炎此前已有描述；然而，这种情况在产前发生极为罕见。我们报告了一名在妊娠早期因GAS发生产前坏死性子宫肌炎和中毒性休克综合征（TSS）的患者，最终需要进行子宫切除术和双侧卵巢切除术。我们讨论了产前坏死性子宫肌炎这一罕见并发症，以及抗生素治疗和与严重A组链球菌感染相关的TSS的治疗。
