School of Chemistry, Cardiff University, Park Place, main building, Cardiff, UK.
Chem Biol Drug Des. 2018 Feb;91(2):647-650. doi: 10.1111/cbdd.13115. Epub 2017 Nov 3.
Flow chemistry could play a key role in the development of fast‐automated synthesis of peptides and proteins through the quick activation of intermediates for coupling at low concentrations of reagents. The selected examples highlight the role of flow chemistry for the advancements of peptides bond formations.
流动化学可以通过快速激活低浓度试剂偶联的中间体,在快速自动化合成肽和蛋白质的发展中发挥关键作用。所选示例突出了流动化学在肽键形成进展方面的作用。