Heh C W, Sramek J, Herrera J, Costa J
Clinical Research Unit, Metropolitan State Hospital, Norwalk, Calif.
Am J Psychiatry. 1988 Jul;145(7):878-9. doi: 10.1176/ajp.145.7.878.
Carbamazepine alone or carbamazepine plus neuroleptic was administered to 20 chronic schizophrenic patients. Upon abrupt discontinuation two of the 20 patients had exacerbations of their psychoses characterized by paranoia, hostility, and agitation. The authors discuss the possibility of a carbamazepine withdrawal syndrome.
对20例慢性精神分裂症患者单独使用卡马西平或卡马西平联合抗精神病药物进行治疗。在突然停药后,20例患者中有2例病情加重,表现为妄想、敌意和激越。作者讨论了卡马西平撤药综合征的可能性。