Petersen Claus
Department of Pediatric Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hanover, Germany.
Pediatr Surg Int. 2017 Dec;33(12):1255-1261. doi: 10.1007/s00383-017-4156-6. Epub 2017 Oct 5.
Biliary atresia (BA) is a rare disease of unknown origin and unsatisfying outcome. Single, multicenter and national evaluations of epidemiological and outcome data on BA have been periodically published over the course of decades. However, the diversity of the registered parameters and outcome measures impede comparability and cumulative analysis of these very worthwhile studies. Taking into account the fact that BA is a good example of translational research and transition of patients from pediatric surgery and hepatology to transplant surgery and hepatology in general, the interdisciplinary community should make every effort to develop a common platform upon which further activities are conducted. Extending this topic to BA-related diseases might increase the acceptance of research studies and enhance the effectiveness of any recommendations outlined therein. The use of the Internet-based communication platform and registry on http://www.bard-online.com represents the first step in this direction, and the database should be viewed as a helpful tool that guides further activities.
胆道闭锁（BA）是一种病因不明且预后不佳的罕见疾病。数十年来，关于BA的流行病学和预后数据的单中心、多中心及全国性评估报告定期发表。然而，所记录参数和预后指标的多样性阻碍了这些极有价值研究的可比性和累积分析。鉴于BA是转化研究以及患者通常从小儿外科和肝病学过渡到移植外科和肝病学的一个典型例子，跨学科群体应全力打造一个开展进一步活动的共同平台。将这一话题扩展至与BA相关的疾病可能会提高研究的接受度，并增强其中所概述的任何建议的有效性。使用基于互联网的交流平台及http://www.bard-online.com上的注册系统是朝着这个方向迈出的第一步，该数据库应被视为指导进一步活动的有用工具。
