Stiff Rhianwen E, Davies Angharad P, Mason Brendan W, Hutchings Hayley A, Chalmers Rachel M
Swansea University Medical School, Singleton Park, Swansea, Wales, SA2 8PP, UK.
Health Protection, Public Health Wales NHS Trust, Temple of Peace, Cathays Park, Cardiff, Wales, CF10 3NW, UK.
J Med Microbiol. 2017 Nov;66(11):1607-1611. doi: 10.1099/jmm.0.000609. Epub 2017 Oct 6.
We describe a longitudinal study carried out in an adult outbreak-associated cohort to investigate health effects, including post-infectious irritable bowel syndrome, occurring after resolution of acute Cryptosporidium parvum infection. New symptoms self-reported up to 12 months included: weight loss (31 %), abdominal pain (38 %), diarrhoea (33 %), eye pain (9 %), joint pain (33 %), fatigue (22 %) and symptoms consistent with irritable bowel syndrome (IBS) (28 %). Two people were medically diagnosed with IBS. This study describes for the first time sequelae reported by patients up to 12 months after infection with C. parvum, which appear to be similar to those described with C. hominis.
我们描述了一项在与成人疫情相关队列中开展的纵向研究，以调查急性微小隐孢子虫感染消退后出现的健康影响，包括感染后肠易激综合征。自我报告的长达12个月的新症状包括：体重减轻（31%）、腹痛（38%）、腹泻（33%）、眼痛（9%）、关节痛（33%）、疲劳（22%）以及符合肠易激综合征（IBS）的症状（28%）。有两人被医学诊断为IBS。本研究首次描述了微小隐孢子虫感染患者在感染后长达12个月报告的后遗症，这些后遗症似乎与微小隐孢子虫感染所描述的后遗症相似。
