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与严重围产期脑损伤相关的母体假性巴特综合征

Maternal Pseudo-Bartter Syndrome Associated with Severe Perinatal Brain Injury.

作者信息

Vora Shrenik, Ibrahim Thowfique, Rajadurai Victor Samuel

机构信息

Department of Neonatology, KK Women's and Children's Hospital, 100, Bukit Timah Road, Singapore. Correspondence to: Dr Shrenik Vora, Senior Staff Registrar, Department of Neonatology, KK Women's and Children's Hospital, 100, Bukit Timah Road, Singapore 229899,

出版信息

Indian Pediatr. 2017 Sep 15;54(9):771-773. doi: 10.1007/s13312-017-1173-4.

Abstract

BACKGROUND

Maternal electrolyte imbalance is rarely reported as causative factor of severe perinatal brain injury.

CASE CHARACTERISTICS

This case outlines a unique maternal and neonatal pseudo-Bartter syndrome presented with metabolic alkalosis and hypochloremia due to maternal severe vomiting.

OBSERVATION

Neonatal MRI brain revealed extensive brain hemorrhages with porencephalic cysts. Subsequent investigation workup points towards maternal severe metabolic alkalosis as its cause.

MESSAGE

Careful medical attention should be paid to pregnant women with excessive vomiting to ensure a healthy outcome for both the mother and the baby.

摘要

背景

孕产妇电解质失衡作为严重围产期脑损伤的致病因素鲜有报道。

病例特征

本病例概述了一种独特的母婴假性巴特综合征,因母亲严重呕吐导致代谢性碱中毒和低氯血症。

观察结果

新生儿脑部磁共振成像显示广泛的脑内出血伴脑穿通性囊肿。后续调查研究表明母亲严重的代谢性碱中毒是其病因。

启示

对于呕吐过度的孕妇应给予密切医疗关注,以确保母婴均有健康的结局。

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