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热干地区运动诱发的支气管痉挛:哮喘、鼻炎和无症状青少年的研究。

Exercise-induced bronchospasm in a hot and dry region: study of asthmatic, rhinitistic and asymptomatic adolescents.

机构信息

a Postgraduate program in hebiatrics , Universidade de Pernambuco , Recife , Brazil.

b Postgraduate Program in Child and Adolescent Health , Universidade Federal de Pernambuco , Recife , Brazil.

出版信息

Expert Rev Respir Med. 2017 Dec;11(12):1013-1019. doi: 10.1080/17476348.2017.1389278. Epub 2017 Oct 10.

DOI:10.1080/17476348.2017.1389278
PMID:28984485
Abstract

BACKGROUND

Exercise-induced bronchospasm (EIB) is the bronchial narrowing that occurs after intense exercise in a significant number of asthmatics and in some non-asthmatics. This study aims to evaluate the occurrence of EIB in adolescents with asthma, rhinitis and respiratory asymptomatics in a hot and dry climate.

RESEARCH DESIGN AND METHODS

This is a cross-sectional study based on an epidemiological study that evaluated the prevalence of asthma in schoolchildren in a semi-arid zone of Brazil. The EIB was defined as a reduction in forced expiratory volume in first second (FEV) greater than 10%.

RESULTS

A total of 114 individuals participated in the study (36.8% male), of whom 54 were asymptomatic, 30 asthmatic and 30 with rhinitis. Asthmatics presented a higher proportion of EIB in comparison to rhinitis and asymptomatics (46.7% vs. 13.3% and 7.4%, p = 0.001) and none of the individuals had severe EIB (ΔFEV ≥ 50%).

CONCLUSIONS

A large proportion of the asthmatics selected from the community for the clinical study had EIB. Among participants with rhinitis, EIB was found in slightly more than 10%, while in the asymptomatics the frequency was slightly more than 5%. This study presents an important aspect in individuals living in hot and dry climates.

摘要

背景

运动诱发的支气管痉挛(EIB)是指在大量哮喘患者和一些非哮喘患者剧烈运动后发生的支气管狭窄。本研究旨在评估在炎热干燥气候下,患有哮喘、鼻炎和呼吸无症状的青少年中 EIB 的发生情况。

研究设计和方法

这是一项基于流行病学研究的横断面研究,评估了巴西半干旱地区学龄儿童哮喘的患病率。EIB 定义为用力呼气第一秒容积(FEV)下降超过 10%。

结果

共有 114 人参与了这项研究(36.8%为男性),其中 54 人无症状,30 人患有哮喘,30 人患有鼻炎。与鼻炎和无症状患者相比,哮喘患者的 EIB 比例更高(46.7%比 13.3%和 7.4%,p=0.001),并且没有患者出现严重的 EIB(ΔFEV≥50%)。

结论

从临床研究中选择的社区哮喘患者中,有很大一部分存在 EIB。在患有鼻炎的参与者中,EIB 的发现率略高于 10%,而在无症状患者中,EIB 的发现率略高于 5%。本研究提出了一个在炎热干燥气候下生活的个体的重要方面。

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J Clin Med. 2024 Aug 5;13(15):4558. doi: 10.3390/jcm13154558.
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Impact of climate variability on exercise-induced bronchospasm in adolescents living in a semi-arid region.气候变异性对居住在半干旱地区青少年运动性支气管痉挛的影响。
Einstein (Sao Paulo). 2021 Sep 27;19:eAO5744. doi: 10.31744/einstein_journal/2021AO5744. eCollection 2021.
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Thermosensory Transient Receptor Potential Ion Channels and Asthma.
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Biomedicines. 2021 Jul 14;9(7):816. doi: 10.3390/biomedicines9070816.
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Exercise-induced bronchoconstriction: prevalence, pathophysiology, patient impact, diagnosis and management.运动诱发性支气管收缩:患病率、病理生理学、患者影响、诊断和管理。
NPJ Prim Care Respir Med. 2018 Aug 14;28(1):31. doi: 10.1038/s41533-018-0098-2.