aDepartment of Critical Care Medicine bCenter for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Curr Opin Crit Care. 2017 Dec;23(6):533-540. doi: 10.1097/MCC.0000000000000451.
Rapid restoration of tissue perfusion and oxygenation are the main goals in the resuscitation of a patient with circulatory collapse. This review will focus on providing an evidence based framework of the technological and conceptual advances in the evaluation and management of the patient with cardiovascular collapse.
The initial approach to the patient in cardiovascular collapse continues to be based on the Ventilate-Infuse-Pump rule. Point of care ultrasound is the preferred modality for the initial evaluation of undifferentiated shock, providing information to narrow the differential diagnosis, to assess fluid responsiveness and to evaluate the response to therapy. After the initial phase of resuscitative fluid administration, which focuses on re-establishing a mean arterial pressure to 65 mmHg, the use of dynamic parameters to assess preload responsiveness such as the passive leg raise test, stroke volume variation, pulse pressure variation and collapsibility of the inferior vena cava in mechanically ventilated patients is recommended.
The crashing patient remains a clinical challenge. Using an integrated approach with bedside ultrasound, dynamic parameters for the evaluation of fluid responsiveness and surrogates of evaluation of tissue perfusion have made the assessment of the patient in shock faster, safer and more physiologic.
快速恢复组织灌注和氧合是治疗循环衰竭患者的主要目标。本综述将重点介绍评估和管理心血管衰竭患者方面的技术和概念进展的循证框架。
心血管衰竭患者的初始治疗方法仍然基于通气-输液-泵规则。床边超声是鉴别诊断不明原因休克的首选方法,提供信息以缩小鉴别诊断范围,评估液体反应性,并评估治疗反应。在复苏输液的初始阶段后,重点是将平均动脉压恢复至 65mmHg,建议使用动态参数评估前负荷反应性,如被动抬腿试验、每搏量变异、脉搏压变异和机械通气患者下腔静脉塌陷。
危重患者仍然是临床挑战。使用床边超声的综合方法、评估液体反应性的动态参数和组织灌注的替代指标,使休克患者的评估更快、更安全、更符合生理。