糖尿病药物与心血管结局试验：经验教训。

Diabetes medications and cardiovascular outcome trials: Lessons learned.

机构信息

Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

出版信息

Cleve Clin J Med. 2017 Oct;84(10):759-767. doi: 10.3949/ccjm.84gr.17006.

DOI:10.3949/ccjm.84gr.17006

PMID:28985176

Abstract

The US Food and Drug Administration's current standards require that new diabetes medications demonstrate cardiovascular safety in large, long-term trials. New drugs that have been assessed in such trials are changing the management of type 2 diabetes.

摘要

美国食品和药物管理局目前的标准要求新的糖尿病药物在大型长期试验中证明心血管安全性。已经在这些试验中评估的新药正在改变 2 型糖尿病的治疗方法。