Mohite Prashant N, Rosenberg Alexander, Caballero Clara Hernández, Soresi Simona, Fatullayev Javid, Reed Anna, Popov Aron-Frederik, Sabashnikov Anton, Simon André R
Department of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, Harefield, UK.
Perfusion. 2017 Oct;32(7):606-608. doi: 10.1177/0267659117702440. Epub 2017 Mar 23.
Extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (LTx) is not uncommon, but it is not commonplace yet. We present a case of a 45-year-old man with cystic fibrosis with recent deterioration in lung function who was initially supported with veno-venous (VV) ECMO. However, he subsequently required conversion to veno-veno-arterial (VVA) ECMO. After 21 days of support, he underwent double lung transplantation, with an uneventful postoperative course. This case shows that, in patients with end-stage respiratory failure awaiting lung transplantation, extracorporeal life support may require escalation to improve gas exchange and address circulatory requirements.
体外膜肺氧合（ECMO）作为肺移植（LTx）的过渡手段并不罕见，但尚未达到常见的程度。我们报告一例45岁的囊性纤维化男性患者，其肺功能近期恶化，最初接受静脉-静脉（VV）ECMO支持。然而，他随后需要转换为静脉-静脉-动脉（VVA）ECMO。在接受21天的支持治疗后，他接受了双肺移植，术后过程平稳。该病例表明，在等待肺移植的终末期呼吸衰竭患者中，体外生命支持可能需要升级以改善气体交换并满足循环需求。
