Georgy Mark, Stern Mark, Murphy Kieran
Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California; Southern California Institute of Neurological Surgery, Escondido, California.
Southern California Institute of Neurological Surgery, Escondido, California.
Can Assoc Radiol J. 2017 Nov;68(4):419-424. doi: 10.1016/j.carj.2017.07.004. Epub 2017 Oct 3.
This review presents a summary of the pathology and epidemiology of Modic changes and the possible role of Propionibacterium acnes. This information is followed by a synthesis of the most recent clinical research involved in culturing the discs of patients with degenerative disc disease for the presence of bacteria. We also discuss a randomized controlled trial that investigates the effects of antibiotics on patients with chronic low back pain and type 1 Modic changes. We conclude with a brief discussion of the difficulties involved in this research and the significance of the findings.
本综述总结了Modic改变的病理学和流行病学以及痤疮丙酸杆菌可能发挥的作用。在此信息之后，综合了最近有关培养退行性椎间盘疾病患者椎间盘以检测细菌存在情况的临床研究。我们还讨论了一项随机对照试验，该试验研究了抗生素对慢性下腰痛和1型Modic改变患者的影响。我们最后简要讨论了这项研究中涉及的困难以及研究结果的意义。
