Wattjes M P, Fischmann A, Fischer D
Institut für Diagnostische und Interventionelle Neuroradiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Hirslanden Klinik St. Anna, St. Anna-Str. 32, 6006, Luzern, Schweiz.
Radiologe. 2017 Dec;57(12):1005-1011. doi: 10.1007/s00117-017-0309-9.
Imaging, in particular magnetic resonance imaging (MRI), has in recent years increasingly become a crucial tool for the diagnostics of inherited and acquired muscular diseases. The aim of imaging in neuromuscular disorders goes beyond the detection and quantification of degenerative muscular changes, such as fatty degeneration and includes recognition of very early signs of muscular pathologies presenting as muscular edema. Therefore, imaging is a valuable diagnostic method to support the clinical diagnosis and to narrow down the differential diagnoses, leading to specific additional diagnostic tests in order to establish the correct diagnosis. Although advances in MRI hardware and technology have led to a faster, more accurate and advanced image acquisition allowing whole body examination in a feasible fashion, the standardization of image acquisition and interpretation remains a challenge. The aim of this review article is to address the important and clinically relevant issues concerning the role of imaging of neuromuscular diseases in order to facilitate a good interdisciplinary management for the diagnostics and monitoring of neuromuscular diseases.
近年来,成像技术,尤其是磁共振成像(MRI),已日益成为诊断遗传性和后天性肌肉疾病的关键工具。神经肌肉疾病成像的目的不仅在于检测和量化退行性肌肉变化,如脂肪变性,还包括识别表现为肌肉水肿的肌肉病变的极早期迹象。因此,成像技术是一种有价值的诊断方法,有助于支持临床诊断并缩小鉴别诊断范围,从而进行特定的额外诊断测试以确立正确诊断。尽管MRI硬件和技术的进步使得图像采集更快、更准确且更先进,能够以可行的方式进行全身检查,但图像采集和解读的标准化仍然是一项挑战。本文综述的目的是探讨与神经肌肉疾病成像作用相关的重要且临床相关的问题,以便为神经肌肉疾病的诊断和监测提供良好的跨学科管理。