神经肌肉疾病中的骨骼肌成像

Skeletal muscle imaging in neuromuscular disease.

作者信息

Simon Neil G, Noto Yu-Ichi, Zaidman Craig M

机构信息

St Vincent's Clinical School, University of New South Wales, Level 5 deLacy Building, St Vincent's Hospital, Victoria Street, Darlinghurst, NSW 2010, Australia; Department of Neurology, St Vincent's Hospital, Darlinghurst, NSW, Australia.

Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan; Brain and Mind Centre, Sydney Medical School, The University of Sydney, NSW, Australia.

出版信息

J Clin Neurosci. 2016 Nov;33:1-10. doi: 10.1016/j.jocn.2016.01.041. Epub 2016 Sep 6.

DOI:10.1016/j.jocn.2016.01.041

PMID:27612670

Abstract

Skeletal muscle imaging is increasingly used as a complement to clinical and electrophysiological examination in neuromuscular disease. Ultrasound and MRI have developed as the modalities of choice, each with strengths and limitations. Characteristic changes of muscle denervation and myopathy are seen on imaging which may delineate the nature of the disease process or help guide muscle biopsy. Identifying patterns of muscle involvement in hereditary myopathies may inform genetic testing. This review discusses skeletal muscle imaging in neuromuscular disease focusing on practical applications of current and emerging ultrasound and MRI techniques.

摘要

在神经肌肉疾病中，骨骼肌成像越来越多地被用作临床和电生理检查的补充手段。超声和磁共振成像（MRI）已发展成为首选的检查方式，它们各有优缺点。在成像上可以看到肌肉去神经支配和肌病的特征性变化，这可能有助于明确疾病过程的性质或指导肌肉活检。识别遗传性肌病中肌肉受累的模式可为基因检测提供依据。本文综述了神经肌肉疾病中的骨骼肌成像，重点讨论了当前和新兴的超声及MRI技术的实际应用。