Alpha-interferon therapy for essential thrombocythaemia.
作者信息
Giles F J, Singer C R, Gray A G, Yong K L, Brozovic M, Davies S C, Grant I R, Hoffbrand A V, Machin S J, Mehta A B
机构信息
Department of Haematology, University College Hospital, London.
出版信息
Lancet. 1988 Jul 9;2(8602):70-2. doi: 10.1016/s0140-6736(88)90005-0.
PMID:2898699
Abstract
18 patients with symptomatic essential thrombocythaemia were treated with recombinant alpha interferon (2a or 2b). Subcutaneous dosage regimens, which were well-tolerated, selectively lowered the platelet count and relieved symptoms in all patients, whether previously treated or untreated. Recombinant alpha-interferon may offer a non-leukaemogenic alternative therapy for these patients.
摘要
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