Velu T, Delwiche F, Gangji D, Monsieur R, Flament J, Stryckmans P, Wybran J, Bellens R
Oncology. 1985;42 Suppl 1:10-4. doi: 10.1159/000226078.
Human recombinant interferon-alpha 2C was given to 4 patients with essential thrombocythaemia. Three patients achieved a complete remission on day 19 +/- 1 and the 4th achieved a partial remission. After 4 weeks of induction therapy, a maintenance therapy of twice weekly intramuscular injections of 5 X 10(6) or 10 X 10(6) IU was instituted but did not maintain the remission.
将重组人干扰素α-2C给予4例原发性血小板增多症患者。3例患者在第19±1天实现完全缓解,第4例实现部分缓解。诱导治疗4周后,开始每周两次肌肉注射5×10⁶或10×10⁶国际单位的维持治疗,但未能维持缓解状态。