School of Health and Human Performance, Dalhousie University, Halifax, NS, Canada.
Atlantic PATH, Population Cancer Research Program, Dalhousie University, Halifax, NS, Canada.
Prev Med. 2017 Dec;105:326-331. doi: 10.1016/j.ypmed.2017.10.013. Epub 2017 Oct 5.
Owing to an aging population and medical advances, the anticipated growth and prevalence of multimorbidity has been recognized as a significant challenge and priority in health care settings. Although physical activity has been shown to play a vital role in the primary and secondary prevention of chronic disease, much less is known about the relationship between physical activity and multimorbidity. The objective of the present study was to examine the relationship between physical activity levels and multimorbidity in male and female adults after adjusting for key demographic, geographical, and lifestyle factors. The study drew data from a prospective cohort in Atlantic Canada (2009-2015). The sample included 18,709 participants between the ages of 35-69. Eighteen chronic diseases were identified. Physical activity levels were estimated based on the long form of the International Physical Activity Questionnaire. Using logistic regression analysis, we found that multimorbid individuals were significantly more likely to be physically inactive (OR=1.26; 95% CI 1.10, 1.44) after adjusting for key sociodemographic and lifestyle characteristics. Additional stratified analyses suggest that the magnitude of the effect between multimorbidity and physical activity was stronger for men (OR=1.41; 95% CI 1.12, 1.79) than women (OR=1.18; CI 1.00, 1.39) and those living in rural (OR=1.43; CI 1.10, 1.85) versus urban (OR=1.20; CI 1.02, 141) areas. Given the generally low levels of physical activity across populations and a growing prevalence of multimorbidity, there is a need for a prospective study to explore causal associations between physical activity, multimorbidity, and health outcomes.
由于人口老龄化和医疗技术的进步，多病症的预期增长和流行已被认为是医疗保健领域的重大挑战和优先事项。尽管已经证明身体活动在慢性病的一级和二级预防中起着至关重要的作用，但对于身体活动与多病症之间的关系却知之甚少。本研究的目的是在调整关键人口统计学、地理和生活方式因素后，研究身体活动水平与男性和女性成年人多病症之间的关系。该研究的数据来自加拿大大西洋地区的一项前瞻性队列研究（2009-2015 年）。样本包括 35-69 岁的 18709 名参与者。确定了 18 种慢性疾病。身体活动水平是根据国际体力活动问卷的长式来估计的。使用逻辑回归分析，我们发现，在调整关键社会人口统计学和生活方式特征后，多病症患者身体活动不活跃的可能性显著更高（OR=1.26；95%CI 1.10，1.44）。进一步的分层分析表明，在多病症和身体活动之间的效应大小方面，男性（OR=1.41；95%CI 1.12，1.79）强于女性（OR=1.18；CI 1.00，1.39），农村（OR=1.43；CI 1.10，1.85）地区强于城市（OR=1.20；CI 1.02，1.41）地区。鉴于人群中身体活动水平普遍较低，多病症的患病率不断上升，需要进行前瞻性研究来探索身体活动、多病症和健康结果之间的因果关系。
