State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, 100193, China; Chinese Academy of Agricultural Sciences-World Agroforestry Center (CAAS-ICRAF) Joint Lab on Agroforestry and Sustainable Animal Husbandry, World Agroforestry Centre, East and Central Asia, 100081, Beijing; Hunan Co-Innovation Center of Animal Production Safety, CICAPS, Hunan, 410128, China.
J Dairy Sci. 2017 Dec;100(12):9602-9610. doi: 10.3168/jds.2017-12610. Epub 2017 Oct 4.
This study aimed to evaluate the effect of hydroxy-selenomethionine (HMSeBA), a novel organic selenium (Se) source, on milk performance, antioxidative status, and Se concentrations in the milk and plasma of mid-lactation dairy cows compared with that of sodium selenite (SS). Fifty mid-lactation dairy cows with similar days in milk, milk yield, and parity received the same basal diet containing 0.06 mg of Se/kg of DM. They were assigned to 1 of 5 treatments according to a randomized complete block design: negative control (without Se supplementation), SS supplementation (0.3 mg of Se/kg of DM; SS-0.3) or HMSeBA supplementation (0.1, 0.3, or 0.5 mg of Se/kg of DM: SO-0.1, SO-0.3, and SO-0.5, respectively). The experiment lasted for 10 wk, including a pretrial period of 2 wk. The results indicated that neither Se supplementation nor Se source affected dry matter intake, milk yield, milk composition, or blood biochemical parameters, except for milk fat percentage. Simultaneously, milk fat percentage and milk fat yield increased linearly as the quantity of HMSeBA supplementation was increased. Production of 4% FCM and ECM was elevated linearly as dietary HMSeBA increased. The SO-0.3 group showed higher serum activity of glutathione peroxidase, total antioxidant capacity, and superoxide dismutase than the SS-0.3 group, but malondialdehyde content was not affected by Se source. Furthermore, HMSeBA supplementation linearly increased the activities of serum glutathione peroxidase and superoxide dismutase, but decreased malondialdehyde content. Compared with the SS-0.3 group, the SO-0.3 group showed augmented concentrations of total Se in milk and plasma, and total Se milk-to-plasma concentration ratio. In addition, increasing doses of HMSeBA linearly increased the concentrations of total Se in the milk and plasma. This study demonstrates that HMSeBA improves antioxidant status and increases milk and plasma Se concentrations more effectively than SS, indicating that HMSeBA could replace SS as an effective organic Se source for lactating dairy cows.
本研究旨在评估羟硒蛋氨酸（HMSeBA），一种新型的有机硒（Se）来源，对泌乳中期奶牛的产奶性能、抗氧化状态以及奶和血浆中 Se 浓度的影响，与亚硒酸钠（SS）进行比较。50 头处于泌乳中期、产奶量和胎次相近的奶牛接受相同的基础日粮，其中含有 0.06mg/kg DM 的 Se。根据随机完全区组设计，它们被分配到 5 种处理中的 1 种：阴性对照（不补充 Se）、SS 补充（0.3mg/kg DM；SS-0.3）或 HMSeBA 补充（0.1、0.3 或 0.5mg/kg DM：SO-0.1、SO-0.3 和 SO-0.5）。实验持续 10 周，包括 2 周的预试验期。结果表明，无论是 Se 补充还是 Se 来源都不会影响干物质采食量、产奶量、奶成分或血液生化参数，除了乳脂率。同时，随着 HMSeBA 补充量的增加，乳脂率和乳脂产量呈线性增加。随着日粮中 HMSeBA 的增加，4%FCM 和 ECM 的产量呈线性增加。与 SS-0.3 组相比，SO-0.3 组的血清谷胱甘肽过氧化物酶、总抗氧化能力和超氧化物歧化酶活性更高，但丙二醛含量不受 Se 来源的影响。此外，HMSeBA 补充物呈线性增加血清谷胱甘肽过氧化物酶和超氧化物歧化酶的活性，但降低丙二醛的含量。与 SS-0.3 组相比，SO-0.3 组的奶和血浆中总 Se 浓度以及奶-血浆总 Se 浓度比均增加。此外，HMSeBA 剂量的增加呈线性增加奶和血浆中总 Se 的浓度。本研究表明，HMSeBA 可改善抗氧化状态，比 SS 更有效地增加奶和血浆中的 Se 浓度，表明 HMSeBA 可以替代 SS 作为泌乳奶牛有效的有机 Se 来源。
