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[使用精神兴奋剂和低剂量抗精神病药治疗成年期注意力缺陷障碍——一则病例报告]

[Treatment of attention deficit disorders in adulthood using psychostimulants and low-dose neuroleptics--a critical case report].

作者信息

Schmidt L G, Schlünder M, Reischies F M

机构信息

Psychiatrische Klinik und Poliklinik, Freien Universität Berlin.

出版信息

Psychiatr Prax. 1988 Mar;15(2):62-5.

PMID:2898788
Abstract

Psychiatric research and therapy recently evinced increasing interest in patients suffering from attention deficit disorder. "Attention deficit disorder" is a category of mental disorders listed in DSM III, with a separate diagnostic subgroup for attention deficit disorders persisting in adults who had been hyperkinetic in childhood ("attention deficit disorder-residual type"); however, this does not feature in a corresponding manner in the ICD 9 version. Since there are practically no therapy studies in existence within the ICD range that can be relevant for such disorders, we studied the treatment of an adult patient with the psychostimulant fenetylline under clinical conditions and found a significant improvement in attention performance. However, on integration in a long-term day-clinic rehabilitation programme we found that low-dose neuroleptic treatment was on the whole of greater benefit than fenetylline treatment.

摘要

精神病学研究与治疗领域近来对患有注意力缺陷障碍的患者表现出越来越浓厚的兴趣。“注意力缺陷障碍”是《精神疾病诊断与统计手册》第三版(DSM III)中列出的一类精神障碍,对于童年期有多动症状的成年人持续存在的注意力缺陷障碍有一个单独的诊断亚组(“注意力缺陷障碍残留型”);然而,在国际疾病分类第九版(ICD 9)版本中没有以相应的方式体现这一点。由于在ICD范围内实际上不存在与这类障碍相关的治疗研究,我们在临床条件下研究了用精神振奋剂非尼乙胺治疗一名成年患者的情况,发现其注意力表现有显著改善。然而,在纳入一个长期日间门诊康复项目后,我们发现低剂量抗精神病药物治疗总体上比非尼乙胺治疗更有益。

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