Lenca Nicole, Poole Colin F
Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
J Chromatogr A. 2017 Nov 17;1524:210-214. doi: 10.1016/j.chroma.2017.09.064. Epub 2017 Sep 28.
The solvation parameter model is used to construct a system map for the retention of volatile organic compounds on the ionic liquid stationary phase tri(tripropypphosphoniumhexanamido)triethylamine bis(trifluoromethylsulfonyl)imide (SLB-IL76) over the temperature range 80-240°C. The SLB-IL76 stationary phase is moderately cohesive and strongly dipolar/polarizable and hydrogen-bond basic but only a weak hydrogen-bond acid. Electron lone pair interactions are weak and make only a minor contribution to the retention mechanism. The separation properties of SLB-IL76 highlight the difficulty of designing new stationary phases from ion structures as the presence of amide groups in the cation don't seem to contribute significantly to the hydrogen-bond acidity of SLB-IL76. The separation properties of SLB-IL76 are closest to the bis(polycyanopropyl)siloxane stationary phases with a high percentage of bis(cyanopropyl)siloxane monomer and could be used in method development when a stationary phase with similar gross retention characteristics but different selectivity is required.
溶剂化参数模型用于构建在80 - 240°C温度范围内挥发性有机化合物在离子液体固定相三（三丙基膦酰己酰胺）三乙胺双（三氟甲基磺酰）亚胺（SLB - IL76）上保留的系统图谱。SLB - IL76固定相具有适度的内聚性、强偶极/可极化性且是氢键碱，但只是弱氢键酸。电子孤对相互作用较弱，对保留机制的贡献较小。SLB - IL76的分离特性凸显了从离子结构设计新型固定相的困难，因为阳离子中酰胺基团的存在似乎对SLB - IL76的氢键酸性贡献不大。SLB - IL76的分离特性与含有高比例双（氰丙基）硅氧烷单体的双（聚氰丙基）硅氧烷固定相最为接近，当需要具有相似总体保留特性但选择性不同的固定相时，可用于方法开发。
