Slynarski Konrad, Walawski Jacek, Smigielski Robert, van der Merwe Willem
Lekmed Medical Center, Warsaw, Poland.
Centrum Medyczne Gamma Hospital, Warsaw, Poland.
Clin Med Insights Arthritis Musculoskelet Disord. 2017 Sep 27;10:1179544117733446. doi: 10.1177/1179544117733446. eCollection 2017.
In young patients with medial knee osteoarthritis (OA), surgical intervention may not be desirable due to preferences to avoid bone cutting procedures, return to high activity levels, and prolong implant survival. The Atlas Knee System was designed to fill the gap between ineffective conservative treatments and invasive surgery. This single-arm study included 26 patients, aged 25 to 65 years, who completed 12 months of follow-up. All dimensions of the Knee injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Knee Society Score significantly improved from baseline to 12 months. About 96.2% and 92.3% of patients experienced a ⩾20% improvement in their KOOS pain and WOMAC pain scores, respectively, at 12 months. This study highlights the potential benefit of a joint unloading device in the management of young patients with medial knee OA. The trial is still ongoing and another analysis is planned at 24 months.
在患有膝关节内侧骨关节炎（OA）的年轻患者中，由于倾向于避免进行截骨手术、恢复高活动水平以及延长植入物使用寿命，手术干预可能并非理想选择。阿特拉斯膝关节系统旨在填补无效保守治疗与侵入性手术之间的空白。这项单臂研究纳入了26名年龄在25至65岁之间且完成了12个月随访的患者。膝关节损伤和骨关节炎疗效评分（KOOS）、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）以及膝关节协会评分的所有维度从基线到12个月均有显著改善。在12个月时，分别约有96.2%和92.3%的患者KOOS疼痛评分和WOMAC疼痛评分改善了⩾20%。本研究强调了关节卸载装置在治疗年轻膝关节内侧OA患者中的潜在益处。该试验仍在进行中，计划在24个月时进行另一项分析。
