Tverskaia M S, Kositskiĭ G I
Biull Eksp Biol Med. 1988 Jun;105(6):690-2.
The effects of cordanum and propranolol on the coronary resistance were studied in isolated cat hearts. The infusion of cordanum and propranolol may be followed by both reduction or enlargement of the coronary resistance. The alterations of the coronary resistance are in most cases parallel with the weakening of the isolated heart function. In some cases cordanum infusion is followed by a short-term reduction in the coronary resistance, which precedes the alteration of the heart function and thus may be due to direct cordanum effect on the coronary vessels.
在离体猫心实验中研究了可多胺和普萘洛尔对冠状动脉阻力的影响。输注可多胺和普萘洛尔后,冠状动脉阻力可能降低或增大。在大多数情况下,冠状动脉阻力的改变与离体心脏功能减弱平行。在某些情况下,输注可多胺后冠状动脉阻力会出现短期降低,这发生在心脏功能改变之前,因此可能是可多胺对冠状动脉血管的直接作用所致。