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松果体区胶质母细胞瘤:4例报告及文献复习

Glioblastoma of pineal region: report of four cases and literature review.

作者信息

Orrego Enrique, Casavilca Sandro, Garcia-Corrochano Pamela, Rojas-Meza Sugey, Castillo Miluska, Castaneda Carlos A

机构信息

Department of Neurosurgery, Instituto Nacional de Enfermedades Neoplasicas, 15038 Lima, Peru.

Department of Pathology, Instituto Nacional de Enfermedades Neoplasicas, 15038 Lima, Peru.

出版信息

CNS Oncol. 2017 Oct;6(4):251-259. doi: 10.2217/cns-2016-0047. Epub 2017 Oct 9.

Abstract

We report four cases of glioblastoma in the pineal region. The patients presented a severe headache and vomiting. Brain imaging showed a heterogeneously enhanced tumor in the pineal region with obstructive hydrocephalus. Case 3 developed a subependymal dissemination. The patient went to ventricular-peritoneal shunt and subtotal or total resection and radiotherapy with/without chemotherapy. Cases 1 and 2 received radiation and died 8 and 11 later months. Cases 3 and 4 completed radiotherapy and chemotherapy, and survived 28 and 31 months after the initial diagnosis. Glioblastoma in the pineal region carry a poor prognosis and require neurooncology teams.

摘要

我们报告了4例松果体区胶质母细胞瘤。患者均出现严重头痛和呕吐。脑部影像学检查显示松果体区有不均匀强化的肿瘤,并伴有梗阻性脑积水。病例3发生了室管膜下播散。该患者接受了脑室-腹腔分流术及次全或全切除术,并接受了放疗,可选择联合或不联合化疗。病例1和病例2接受了放疗,分别于8个月和11个月后死亡。病例3和病例4完成了放疗和化疗,在初次诊断后分别存活了

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本文引用的文献

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Primary pineal glioblastoma: a case report.原发性松果体胶质母细胞瘤:一例报告。
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The 2007 WHO classification of tumours of the central nervous system.2007年世界卫生组织中枢神经系统肿瘤分类
Acta Neuropathol. 2007 Aug;114(2):97-109. doi: 10.1007/s00401-007-0243-4. Epub 2007 Jul 6.
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