Auvinen Piritta, Mäntyselkä Pekka, Koponen Hannu, Kautiainen Hannu, Korniloff Katariina, Ahonen Tiina, Vanhala Mauno
a Institute of Public Health and Clinical Nutrition, General Practice Unit , University of Eastern Finland , Kuopio , Finland.
b Primary Health Care Unit , Kuopio University Hospital , Kuopio , Finland.
Nord J Psychiatry. 2018 Jan;72(1):51-56. doi: 10.1080/08039488.2017.1385849. Epub 2017 Oct 9.
Restless legs syndrome is a sensorimotor disorder and it is associated with several other diseases especially mental illnesses.
To analyze the relationship between the symptoms of restless legs syndrome and the severity of depressive symptoms and the prevalence of restless legs symptoms in depression subtypes.
A cross-sectional study of primary care patients in the Central Finland Hospital District. The prevalence of restless legs symptoms was studied in 706 patients with increased depressive symptoms and 426 controls without a psychiatric diagnosis by using a structured questionnaire. The depressive symptoms were evaluated with the Beck Depression Inventory (BDI) and the psychiatric diagnosis was confirmed by means of a diagnostic interview (Mini-International Neuropsychiatric Interview). The subjects with increased depressive symptoms were divided into three groups (subjects with depressive symptoms without a depression diagnosis, melancholic depression and non-melancholic depression).
In the whole study population, the prevalence of restless legs symptoms increased with the severity of depressive symptoms. The prevalence of restless legs symptoms was highest in the melancholic and non-melancholic depressive patients (52 and 46%, respectively) and then in subjects with depressive symptoms without a depression diagnosis (43.4%), but the prevalence was also substantial (24.6%) in subjects without a psychiatric diagnosis.
Restless legs symptoms are very common in primary care among subjects with depression, regardless of the depression type. The prevalence of restless legs symptoms increased with increasing severity of depressive symptoms, regardless of the diagnosis. These findings should be considered in clinical evaluation and treatment of patients visiting their physician due to restless legs or depressive symptoms.
不宁腿综合征是一种感觉运动障碍，与其他几种疾病尤其是精神疾病有关。
分析不宁腿综合征症状与抑郁症状严重程度之间的关系以及不宁腿症状在抑郁症亚型中的患病率。
对芬兰中部医院区的初级保健患者进行横断面研究。通过使用结构化问卷，对706例抑郁症状加重的患者和426例无精神疾病诊断的对照者进行不宁腿症状患病率的研究。用贝克抑郁量表（BDI）评估抑郁症状，通过诊断性访谈（迷你国际神经精神病学访谈）确认精神疾病诊断。将抑郁症状加重的受试者分为三组（无抑郁症诊断的抑郁症状受试者、 melancholic抑郁症和非melancholic抑郁症）。
在整个研究人群中，不宁腿症状的患病率随抑郁症状的严重程度增加而升高。不宁腿症状的患病率在melancholic和非melancholic抑郁症患者中最高（分别为52%和46%），其次是无抑郁症诊断的抑郁症状受试者（43.4%），但在无精神疾病诊断的受试者中患病率也较高（24.6%）。
在初级保健中，无论抑郁症类型如何，不宁腿症状在抑郁症患者中都非常常见。不宁腿症状的患病率随抑郁症状严重程度的增加而升高，无论诊断如何。在对因不宁腿或抑郁症状就诊的患者进行临床评估和治疗时，应考虑这些发现。
