腹腔镜中转或原发性开放切除术后结直肠癌的长期肿瘤学结局：文献系统评价
Long-term Oncologic Outcome After Laparoscopic Converted or Primary Open Resection for Colorectal Cancer: A Systematic Review of the Literature.
作者信息
Furnée Edgar J B, Allaix Marco E, Morino Mario
机构信息
*Department of Surgical Sciences, University of Torino, Turin, Italy †Department of Abdominal Surgery, University Medical Centre, Groningen, The Netherlands.
出版信息
Surg Laparosc Endosc Percutan Tech. 2017 Oct;27(5):328-334. doi: 10.1097/SLE.0000000000000420.
PURPOSE
The aim of this study was to critically review the current evidence regarding the oncologic outcomes after laparoscopic converted or open resection for colorectal cancer.
MATERIALS AND METHODS
A literature search was performed in Pubmed. Study selection and data acquisition were independently performed by 2 reviewers.
RESULTS
The search strategy yielded a total of 746 articles, resulting in 7 studies eligible for inclusion. A total of 9190 (57 to 8307) patients were included in the open and 238 (17 to 56) in the converted group. In none of the studies, differences were found in disease stage between both groups. There were no significant differences between both groups with regard to overall survival, local recurrence and distant metastasis rate.
CONCLUSIONS
There is currently insufficient evidence that patients who had a laparoscopic resection for colorectal cancer converted to open surgery have a worse oncologic outcome than patients who were primarily treated by an open approach.
目的
本研究旨在严格审查目前关于腹腔镜中转开腹或开腹切除术后结直肠癌肿瘤学结局的证据。
材料与方法
在PubMed上进行文献检索。由2名审阅者独立进行研究选择和数据收集。
结果
检索策略共产生746篇文章，最终纳入7项研究。开腹组共纳入9190例（57至8307例）患者，中转组纳入238例（17至56例）患者。在所有研究中，两组之间的疾病分期均无差异。两组在总生存率、局部复发率和远处转移率方面均无显著差异。
结论
目前尚无充分证据表明，结直肠癌腹腔镜切除中转开腹手术患者的肿瘤学结局比直接采用开腹手术治疗的患者更差。
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