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儿童罹患侵袭性肺炎球菌病风险人群中抗生素的不成比例暴露：新兴耐药性的潜在风险与抗生素管理的机会。

Disproportionate Exposure to Antibiotics in Children at Risk for Invasive Pneumococcal Disease: Potential for Emerging Resistance and Opportunity for Antibiotic Stewardship.

机构信息

Section of Infectious Diseases, Boston University School of Medicine, Massachusetts.

Center for Global Health and Development, Boston University School of Public Health, Massachusetts.

出版信息

J Pediatric Infect Dis Soc. 2019 Mar 28;8(1):63-65. doi: 10.1093/jpids/pix070.

DOI:10.1093/jpids/pix070
PMID:28992176
Abstract

We compared antibiotic prescribing for children with and those without an underlying chronic condition associated with increased risk for invasive pneumococcal disease. Children with a chronic condition had significantly greater cumulative exposure to antibiotics and higher rates of prescriptions per person-year than those without a chronic condition; this population is at increased risk for the emergence of multidrug-resistant pathogens.

摘要

我们比较了患有和不患有与侵袭性肺炎球菌病风险增加相关的潜在慢性疾病的儿童的抗生素处方情况。患有慢性疾病的儿童接受抗生素的累积暴露量明显更高，且每人每年的处方率也高于没有慢性疾病的儿童；这一人群出现多种耐药病原体的风险增加。

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