Kanda Sohei, Okubo Kazutoshi, Hida Takuya, Kono Jin, Takahashi Takeshi, Mitsumori Kenji, Shimada Toshihide, Nishimura Kazuo
The Department of Urology, Osaka Red Cross Hospital.
The Department of Diagnostic Pathology, Osaka Red Cross Hospital.
Hinyokika Kiyo. 2017 Sep;63(9):381-386. doi: 10.14989/ActaUrolJap_63_9_381.
We present a case of secondary extramammary Paget's disease around the cutaneous ureterostomy stoma after radical cystectomy. An 85-year-old man with bacillus calmette-guérin refractory high-grade urothelial carcinoma underwent radical cystectomy and cutaneous ureterostomy construction. After right ureter cancer diagnosis, he underwent right nephroureterectomy 3 years after the cystectomy. He developed refractory dermatitis around the cutaneous stoma 1 year after the nephroureterectomy. Skin biopsy revealed secondary extramammary Paget's disease, cured by skin excision around the cutaneous stoma and skin grafting. Multiple urothelial carcinoma metastases were detected 6 months later ; he died of urothelial cancer 1 month later.
我们报告1例根治性膀胱切除术后皮肤输尿管造口周围继发性乳腺外佩吉特病的病例。一名85岁男性,患有卡介苗难治性高级别尿路上皮癌,接受了根治性膀胱切除术并构建了皮肤输尿管造口。膀胱切除术后3年,在诊断出右侧输尿管癌后,他接受了右侧肾输尿管切除术。肾输尿管切除术后1年,他在皮肤造口周围出现难治性皮炎。皮肤活检显示为继发性乳腺外佩吉特病,通过切除皮肤造口周围皮肤及植皮治愈。6个月后检测到多发尿路上皮癌转移;1个月后他死于尿路上皮癌。