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[一名17岁男性服用异维A酸后发生横纹肌溶解症]

[Rhabdomyolysis after isotretinoin treatment in a 17-year-old male].

作者信息

Paulsrud Cecilie, Stender Ida-Marie, Schmidt Lisbeth Samsø

出版信息

Ugeskr Laeger. 2017 Oct 2;179(40).

PMID:28992847
Abstract

Rhabdomyolysis is a rare, but known complication to treat-ment with systemic isotretinoin in patients with acne and can lead to severe kidney damage. In our case report a 17-year-old male, exercising moderately, developed rhab-domyolysis without kidney injury after two-month treatment with isotretinoin 20 mg daily. He complained of some muscle pain and was treated according to guidelines for rhabdomyolysis with no sequelae. Frequent monitoring of muscle complaints and control of serum creatine kinase in patients with affected liver and kidney function is essential.

摘要

横纹肌溶解症是一种罕见但已知的痤疮患者全身使用异维A酸治疗的并发症,可导致严重的肾损伤。在我们的病例报告中,一名17岁的男性,适度运动,在每日服用20毫克异维A酸治疗两个月后出现了无肾损伤的横纹肌溶解症。他主诉有一些肌肉疼痛,并按照横纹肌溶解症的治疗指南进行治疗,无后遗症。对肝肾功能受损患者频繁监测肌肉不适并控制血清肌酸激酶至关重要。

相似文献

1
[Rhabdomyolysis after isotretinoin treatment in a 17-year-old male].[一名17岁男性服用异维A酸后发生横纹肌溶解症]
Ugeskr Laeger. 2017 Oct 2;179(40).
2
Clinical significance of markedly elevated serum creatine kinase levels in patients with acne on isotretinoin.异维A酸治疗痤疮患者血清肌酸激酶水平显著升高的临床意义
Acta Derm Venereol. 2001 Oct-Nov;81(5):350-2. doi: 10.1080/000155501317140070.
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The creatine kinase conundrum: a reappraisal of the association of isotretinoin, creatine kinase, and rhabdomyolysis.肌酸激酶之谜:异维 A 酸、肌酸激酶和横纹肌溶解症关联性的再评估。
Int J Dermatol. 2020 Mar;59(3):279-283. doi: 10.1111/ijd.14758. Epub 2019 Dec 27.
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Acute rhabdomyolysis and myoglobinuria associated with isotretinoin treatment.异维A酸治疗相关的急性横纹肌溶解症和肌红蛋白尿
Int J Dermatol. 2003 Jun;42(6):499-500. doi: 10.1046/j.1365-4362.2003.01917.x.
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Creatine phosphokinase values during isotretinoin treatment for acne.异维A酸治疗痤疮期间的肌酸磷酸激酶值
Int J Dermatol. 2008 Apr;47(4):398-401. doi: 10.1111/j.1365-4632.2008.03491.x.
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Acne, isotretinoin and depression.痤疮、异维甲酸与抑郁症。
Drug Ther Bull. 2003 Oct;41(10):76-8. doi: 10.1136/dtb.2003.411076.
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[Panic attacks in a patient treated with isotretinoin for acne. Report of one case].[一名接受异维A酸治疗痤疮的患者出现惊恐发作。病例报告]
Rev Med Chil. 2006 Dec;134(12):1565-7. doi: 10.4067/s0034-98872006001200012. Epub 2007 Jan 24.
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Isotretinoin treatment in patients with acne vulgaris: does it impact muscle strength, fatigue, and endurance?寻常痤疮患者的异维A酸治疗:它会影响肌肉力量、疲劳和耐力吗?
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Eruptive milia during isotretinoin therapy.异维A酸治疗期间出现的发疹性粟丘疹。
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引用本文的文献

1
Isotretinoin Associated Rhabdomyolysis: Monitoring Creatine Kinase and Educating Patients.异维A酸相关性横纹肌溶解症:监测肌酸激酶并对患者进行教育
Skin Appendage Disord. 2021 Nov;7(6):493-498. doi: 10.1159/000517831. Epub 2021 Jul 28.
2
Isotretinoin and the Kidney: Opportunities and Threats.异维A酸与肾脏:机遇与威胁
Clin Cosmet Investig Dermatol. 2020 Jul 28;13:485-494. doi: 10.2147/CCID.S259048. eCollection 2020.