Paulsrud Cecilie, Stender Ida-Marie, Schmidt Lisbeth Samsø
Ugeskr Laeger. 2017 Oct 2;179(40).
Rhabdomyolysis is a rare, but known complication to treat-ment with systemic isotretinoin in patients with acne and can lead to severe kidney damage. In our case report a 17-year-old male, exercising moderately, developed rhab-domyolysis without kidney injury after two-month treatment with isotretinoin 20 mg daily. He complained of some muscle pain and was treated according to guidelines for rhabdomyolysis with no sequelae. Frequent monitoring of muscle complaints and control of serum creatine kinase in patients with affected liver and kidney function is essential.
横纹肌溶解症是一种罕见但已知的痤疮患者全身使用异维A酸治疗的并发症,可导致严重的肾损伤。在我们的病例报告中,一名17岁的男性,适度运动,在每日服用20毫克异维A酸治疗两个月后出现了无肾损伤的横纹肌溶解症。他主诉有一些肌肉疼痛,并按照横纹肌溶解症的治疗指南进行治疗,无后遗症。对肝肾功能受损患者频繁监测肌肉不适并控制血清肌酸激酶至关重要。