Vannorsdall Tracy D
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 218, Baltimore, MD 21287, USA; Department of Neurology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 218, Baltimore, MD 21287, USA.
Med Clin North Am. 2017 Nov;101(6):1115-1134. doi: 10.1016/j.mcna.2017.06.006. Epub 2017 Aug 25.
A growing population of cancer survivors is at risk for acute and long-term consequences resulting from cancer and its treatment. Cancer-related cognitive impairment (CRCI) typically manifests as modest deficits in attention, processing speed, executive functioning, and memory, which may persist for decades after treatment. Although some risk factors for CRCI are largely immutable (eg, genetics and demographic factors), there are many other contributors to CRCI that when appropriately addressed can result in improved cognitive functioning and quality of life. Neuropsychological assessment can help identify patient cognitive strengths and weaknesses, target psychological and behavioral contributors to CRCI, and guide treatment interventions.
越来越多的癌症幸存者面临着癌症及其治疗带来的急性和长期后果的风险。癌症相关的认知障碍（CRCI）通常表现为注意力、处理速度、执行功能和记忆力方面的轻度缺陷，这些缺陷可能在治疗后持续数十年。虽然CRCI的一些风险因素在很大程度上是不可改变的（例如，遗传和人口统计学因素），但CRCI还有许多其他促成因素，若得到适当处理，可改善认知功能和生活质量。神经心理学评估有助于识别患者的认知优势和劣势，确定导致CRCI的心理和行为因素，并指导治疗干预。
