Department of Neurology, The University of Alabama at Birmingham Heersink School of Medicine, Birmingham, Alabama, USA.
Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Cancer Invest. 2024 Sep;42(8):671-681. doi: 10.1080/07357907.2024.2371368. Epub 2024 Jul 15.
Limited research has compared cognition of people with non-central nervous system metastatic cancer (NCM) metastatic brain cancer (BM). This prospective cross-sectional study was comprised 37 healthy controls (HC), 40 NCM, and 61 BM completing 10 neuropsychological tests. The NCM performed below HCs on processing speed and executive functioning tasks, while the BM group demonstrated lower performance across tests. Tasks of processing speed, verbal fluency, and verbal memory differentiated the clinical groups (BM < NCM). Nearly 20% of the NCM group was impaired on three neuropsychological tests whereas approximately 40% of the BM group demonstrated the same level of impairment.
有限的研究比较了非中枢神经系统转移性癌症（NCM）和转移性脑癌（BM）患者的认知能力。这项前瞻性的横断面研究包括 37 名健康对照者（HC）、40 名 NCM 患者和 61 名 BM 患者，他们完成了 10 项神经心理学测试。NCM 患者在处理速度和执行功能任务上的表现低于 HC，而 BM 组在所有测试中的表现都较低。处理速度、语言流畅性和语言记忆任务可以区分临床组（BM<NCM）。NCM 组中有近 20%的患者在三项神经心理学测试中受损，而大约 40%的 BM 组患者表现出相同程度的受损。
