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B 群脑膜炎球菌疾病疫苗接种的利弊。

Pros and cons of vaccination against serogroup B meningococcal disease.

机构信息

División de Medicina Preventiva y Salud Pública, Universidad de Jaén, Jaén, España; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, España.

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, España; Departamento de Medicina, Universidad de Barcelona, Barcelona, España.

出版信息

Med Clin (Barc). 2018 Feb 9;150(3):109-113. doi: 10.1016/j.medcli.2017.07.018. Epub 2017 Oct 7.

Abstract

A vaccine has recently been approved in the EU against meningococcal serogroup B, the main cause of meningococcal disease. There is a fierce debate about the decision regarding a universal vaccination in infants older than 2 months, as recommended by the majority of scientific societies. In western Europe the only country to have included the universal vaccination is the United Kingdom, with a lower incidence of the disease than Ireland. Other countries have also adopted it, such as the Czech Republic, Cuba and certain regions of Italy. Numerous cost-effectiveness studies have been published regarding the vaccination with different assumptions, which have supported the decision not to implant the universal vaccination because it exceeds the will to pay for a health benefit. We discuss the pros and cons of the universal vaccination against meningococcal B, recommended by the Sociedad Española de Pediatría (Spanish Society of Paediatrics), which as yet has not been implemented.

摘要

最近,欧盟批准了一种针对脑膜炎奈瑟菌 B 群的疫苗,该疫苗是脑膜炎的主要病因。对于大多数科学协会推荐的对 2 个月以上婴儿进行普遍接种的决定,存在激烈的争论。在西欧,唯一实施普遍接种的国家是英国,其疾病发病率低于爱尔兰。其他国家也已经采用了这种方法,例如捷克共和国、古巴和意大利的某些地区。针对不同假设的疫苗接种,已经发表了许多成本效益研究,这些研究支持了不进行普遍接种的决定,因为这超出了为健康效益支付的意愿。我们讨论了西班牙儿科学会(Spanish Society of Paediatrics)推荐的普遍接种脑膜炎 B 型疫苗的利弊,该疫苗尚未实施。

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