ANZAC Research Institute, University of Sydney and Concord Hospital, Sydney, New South Wales, Australia; Center of Education and Research on Aging, University of Sydney and Concord Hospital, Sydney, New South Wales, Australia; ARC Center of Excellence in Population Aging Research, University of Sydney, Sydney, New South Wales, Australia.
School of Science and Health, Western Sydney University, Sydney, New South Wales, Australia.
J Am Med Dir Assoc. 2018 Mar;19(3):216-222. doi: 10.1016/j.jamda.2017.08.018. Epub 2017 Oct 6.
The study aimed to examine the contemporaneous temporal association between changes in total physical activity, sports intensity, muscle strengthening exercise, and walking speed as predictors of all-cause, cardiovascular, cancer and other cause-specific mortality in older men.
DESIGN, SETTING, PARTICIPANTS, MEASUREMENTS: Community-dwelling men aged 70 years and older from Concord Health and Aging in Men Project were assessed at baseline (2005-2007, n = 1705), 2 years (n = 1367), and 5 years follow-up (n = 958). At all time points, Physical Activity Scale for the Elderly questionnaire, walking speed over a 6-m walk, and potential confounders were assessed. Mortality was ascertained through the state death registry with a median follow-up of 7 years.
As the Physical Activity Scale for the Elderly score increased by 1 standard deviation over the follow-up period, the relative risk (RR) for mortality was 0.78 [95% confidence interval (CI) 0.69-0.88] for all-cause, 0.66 (95% CI 0.55-0.79) for cardiovascular and 0.75 (95% CI 0.61-0.94) for other cause-specific mortality, but no association was observed in cancer mortality. The RR for undertaking strenuous sports during follow-up was 0.44 (95% CI 0.26-0.72) for all-cause mortality and 0.31 (95% CI 0.13-0.70) for cancer mortality when compared with no sports participation. Increases in walking speed per standard deviation over time were also associated with a decrease in all-cause mortality (RR 0.69, 95% CI 0.61-0.78), with similar associations for cardiovascular (RR 0.60, 95% CI 0.48-0.74), but not cancer mortality.
Older men who engage in strenuous sports and those who increase their walking speed over time may have lower risk of all-cause and some cause-specific mortality.
本研究旨在探讨总身体活动量、运动强度、肌肉强化运动和行走速度变化作为预测因素,与全因、心血管疾病、癌症和其他特定原因死亡率之间的同期时间关联,这些预测因素针对的是老年男性。
设计、地点、参与者、测量方法:来自康科德老龄化男性健康与衰老项目的 70 岁及以上的社区居住男性,在基线(2005-2007 年,n=1705)、2 年(n=1367)和 5 年随访(n=958)时进行评估。在所有时间点,都评估了老年人身体活动量表、6 米步行速度以及潜在的混杂因素。通过州死亡登记处确定死亡率,中位随访时间为 7 年。
在随访期间,老年人身体活动量表评分增加 1 个标准差,全因死亡率的相对风险(RR)为 0.78[95%置信区间(CI)0.69-0.88],心血管疾病死亡率的 RR 为 0.66(95% CI 0.55-0.79),其他特定原因死亡率的 RR 为 0.75(95% CI 0.61-0.94),但癌症死亡率无相关性。与不参加任何运动相比,在随访期间进行剧烈运动的 RR 为全因死亡率 0.44(95% CI 0.26-0.72),癌症死亡率 0.31(95% CI 0.13-0.70)。随着时间的推移,行走速度每增加一个标准差,全因死亡率也呈下降趋势(RR 0.69,95% CI 0.61-0.78),与心血管疾病死亡率(RR 0.60,95% CI 0.48-0.74)的相关性相似,但与癌症死亡率无关。
进行剧烈运动和随着时间的推移增加行走速度的老年男性,全因死亡率和某些特定原因死亡率的风险可能较低。