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Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis.
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Sleeping Beauty insertional mutagenesis screen identifies the pro-metastatic roles of CNPY2 and ACTN2 in hepatocellular carcinoma tumor progression.
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Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.
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Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors.
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Oncogenic plasmid DNA and liver injury agent dictates liver cancer development in a mouse model.
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Dissecting the oncogenic properties of essential RNA-modifying enzymes: a focus on NAT10.
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Advances in transposable elements: from mechanisms to applications in mammalian genomics.
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NAT10 promotes the tumorigenesis and progression of laryngeal squamous cell carcinoma through ac4C modification of FOXM1 mRNA.
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NAT10 regulates mitotic cell fate by acetylating Eg5 to control bipolar spindle assembly and chromosome segregation.
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2
Targeting cAMP/PKA pathway for glycemic control and type 2 diabetes therapy.
J Mol Endocrinol. 2016 Aug;57(2):R93-R108. doi: 10.1530/JME-15-0316. Epub 2016 May 18.
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Near-optimal probabilistic RNA-seq quantification.
Nat Biotechnol. 2016 May;34(5):525-7. doi: 10.1038/nbt.3519. Epub 2016 Apr 4.
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Structural insights into mis-regulation of protein kinase A in human tumors.
Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1374-9. doi: 10.1073/pnas.1424206112. Epub 2015 Jan 20.
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Non-selective beta-blockers may reduce risk of hepatocellular carcinoma: a meta-analysis of randomized trials.
Liver Int. 2015 Aug;35(8):2009-16. doi: 10.1111/liv.12782. Epub 2015 Feb 6.
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Human NAT10 is an ATP-dependent RNA acetyltransferase responsible for N4-acetylcytidine formation in 18 S ribosomal RNA (rRNA).
J Biol Chem. 2014 Dec 26;289(52):35724-30. doi: 10.1074/jbc.C114.602698. Epub 2014 Nov 19.
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Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.
Nat Genet. 2014 Dec;46(12):1267-73. doi: 10.1038/ng.3126. Epub 2014 Nov 2.
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Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics.
ACS Med Chem Lett. 2012 May 8;3(7):602-6. doi: 10.1021/ml300110s. eCollection 2012 Jul 12.

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