Tolksdorf W
Klinik für Anästhesiologie, Medizinische Fakultät der RWTH Aachen.
Anasth Intensivther Notfallmed. 1988 Jun;23(3):127-31.
Benzodiazepines have an anxiolytic, sedative, amnesic, muscle relaxant and anticonvulsive action. An analysis of the literature shows that benzodiazepines are the most important substances for premedication. They are preferred the evening before surgery for sleep induction. At the day of surgery they reduce stress better than any other substances or combinations. The different characteristics of different substances are presented. The way of application is discussed. Benzodiazepines, especially midazolam, offer new perspectives in the premedication of small children. Especially this group of patients remains to be a severe anaesthesiological problem.
苯二氮䓬类药物具有抗焦虑、镇静、失忆、肌肉松弛和抗惊厥作用。文献分析表明，苯二氮䓬类药物是术前用药最重要的药物。它们在手术前一晚用于诱导睡眠更为合适。在手术当天，它们比其他任何药物或药物组合都能更好地减轻应激。介绍了不同药物的不同特性，并讨论了用药方式。苯二氮䓬类药物，尤其是咪达唑仑，为小儿术前用药提供了新的视角。尤其是这组患者仍然是一个严重的麻醉学问题。
