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[抗H2药物问世10年后的消化性溃疡手术]

[Surgery of peptic ulcer 10 years after the introduction of anti-H2 agents].

作者信息

Bartolotta M, Carditello A

机构信息

Istituto di Discipline Chirurgiche Generali e Speciali Université de Messine, Italie.

出版信息

Ann Gastroenterol Hepatol (Paris). 1988 May-Jun;24(3):107-9.

PMID:2899990
Abstract

To evaluate the actual rate of both elective and emergency surgical operations for peptic ulcer, a questionnaire on the incidence of these operations was sent to 60 european departments of digestive surgery. 28 centers entered the trial, with the following results: 1,800 patients operated on; marked decrease of elective operations (100 percent of the centers); High decrease of emergency operations for hemorrhagic ulcer (80 percent of the centers). Decrease of emergency operations for perforation (50 percent of the centers). Decrease of operations for stenosis (70 percent of the centers). No-responders ulcers (ever more rare) and acute complications of patients with acute ulcer (elderly patients, under steroid or chemotherapy or intensive care) represent the resting indications to surgery. These results confirm the decline of surgery ten years after the introduction of H2 receptor antagonists.

摘要

为评估消化性溃疡择期手术和急诊手术的实际发生率,我们向60个欧洲消化外科科室发送了一份关于这些手术发生率的调查问卷。28个中心参与了此次试验,结果如下:1800例患者接受了手术;择期手术显著减少(所有中心均出现);出血性溃疡急诊手术大幅减少(80%的中心);穿孔急诊手术减少(50%的中心);狭窄手术减少(70%的中心)。无反应性溃疡(越来越罕见)以及急性溃疡患者(老年患者、接受类固醇或化疗或重症监护的患者)的急性并发症是目前仅有的手术指征。这些结果证实了H2受体拮抗剂应用十年后手术率的下降。

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