脑组织中生长抑素的死后稳定性
Postmortem stability of somatostatin in brain tissue.
作者信息
Cooper P E, Rahman Q, Phillips T, Tu J
机构信息
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
出版信息
Neurochem Res. 1988 Jun;13(6):513-5. doi: 10.1007/BF00973289.
The stability of somatostatin (SS) in brain tissue was studied in human material obtained post-mortem and in the rat. In both human and rat brain, loss of SS was found to occur in tissue frozen to -70 degrees C. In the rat, this loss varied from 26 to 70 percent depending on the type of tissue processing used. These data suggest that, for the study of SS in post-mortem brain, use of frozen material should be avoided.
在取自尸检的人体材料和大鼠体内研究了生长抑素（SS）在脑组织中的稳定性。在人和大鼠的脑组织中，均发现冷冻至-70摄氏度的组织中生长抑素会减少。在大鼠中，根据所用组织处理类型的不同，这种减少幅度在26%至70%之间。这些数据表明，对于死后脑组织中生长抑素的研究，应避免使用冷冻材料。
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